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Neovascularization in human germ cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor 1-gen-1996 Viglietto, G; Romano, A; Maglione, D; Rambaldi, M; Paoletti, I; Lago, Ct; Califano, D; Monaco, C; Mineo, A; Santelli, G; Manzo, G; Botti, G; Chiappetta, G; Persico, Mg.
Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway 1-gen-2002 Janda, E; Litos, G; Grünert, S; Downward, J; Beug, H
Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance 1-gen-2023 Fattore, Luigi; Cafaro, Giordana; Di Martile, Marta; Campani, Virginia; Sacconi, Andrea; Liguoro, Domenico; Marra, Emanuele; Bruschini, Sara; Stoppoloni, Daniela; Cirombella, Roberto; De Nicola, Francesca; Pallocca, Matteo; Ruggiero, Ciro F; Castaldo, Vittorio; Catizone, Angiolina; Del Bufalo, Donatella; Viglietto, Giuseppe; Vecchione, Andrea; Blandino, Giovanni; Aurisicchio, Luigi; Fanciulli, Maurizio; Ascierto, Paolo A; De Rosa, Giuseppe; Mancini, Rita; Ciliberto, Gennaro
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase 1-gen-2003 Andreozzi, F; Melillo, Rm; Carlomagno, F; Oriente, F; Miele, C; Fiory, F; Santopietro, S; Castellone, Md; Beguinot, F; Santoro, M; Formisano, P
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1 1-gen-2000 Bruni, P; Boccia, A; Baldassarre, G; Trapasso, F; Santoro, M; Chiappetta, G; Fusco, A; Viglietto, G
Raf and TGFbeta - dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin 1-gen-2006 Janda, E; Nevolo, M; Lehmann, K; Downward, J; Beug, H; Grieco, M
RET/PTC oncogene activation is an early event in thyroid carcinogenesis 1-gen-1995 Viglietto, G; Chiappetta, G; MARTINEZ-TELLO, Fj; Fukunaga, Fh; Tallini, G; Rigopoulou, D; Visconti, R; Mastro, A; Santoro, M; Fusco, A
Role of the cAMP and MAPK pathways in the transformation of mouse 3T3 fibroblasts by a TSHR gene constitutively activated by point mutation 1-gen-2000 Duvillard, J. A.; Wicker, R.; Crespo, P.; Russo, D.; Filetti, S.; Gutkind, J. S.; Sarasin, A.; Suarez, H. G.
Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells. 1-gen-2013 Amato, R; Scumaci, D; D'Antona, L; Iuliano, R; Menniti, M; Di Sanzo, M; Faniello, M; Colao, E; Malatesta, P; Zingone, A; Agosti, V; Costanzo, F; Mileo, Am; Paggi, Mg; Lang, F; Cuda, G; Lavia, P; Perrotti, N
Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo 1-gen-2017 Cesarini, V.; Guida, E.; Todaro, F.; Di Agostino, S.; Tassinari, V.; Nicolis, S.; Favaro, R.; Caporali, S.; Lacal, P. M.; Botti, E.; Costanzo, A.; Rossi, P.; Jannini, E. A.; Dolci, S.
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ 1-gen-2017 Noto, A; De Vitis, C; Pisanu, Me; Roscilli, G; Ricci, G; Catizone, A; Sorrentino, G; Chianese, G; Taglialatela-Scafati, O; Trisciuoglio, D; Del Bufalo, D; Di Martile, M; Di Napoli, A; Ruco, L; Costantini, S; Jakopin, Z; Budillon, A; Melino, G; Del Sal, G; Ciliberto, G; Mancini, R
The farnesil transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate 1-gen-2004 Caraglia, M; D'Alessandro, Am; Marra, M; Giuberti, G; Vitale, G; Viscomi, C; Colao, A PRETE SD; Tagliaferri, P; Tassone, P; Budillon, A; Venuta, S; Abbruzzese, A
The farnesyl transferase inhibitor R115777 (Zarnestra (R)) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa (R)) and Pamidronate 1-gen-2004 Caraglia, M; D'Alessandro, Am; Marra, M; Giuberti, G; Vitale, G; Viscomi, C; Colao, A; Del Prete, S; Tagliaferri, P; Tassone, P; Budillon, A; Venuta, S; Abbruzzese, A
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue 1-gen-2005 LE PERA, I; Florio, T; Susini, C; Trapasso, F; Santoro, M; Chiariotti, L; Schettini, G; Fusco, A; Viglietto, G
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid 1-gen-2004 LE PERA, I; Cristofaro, C; Baudi, F; Arturi, F; Pallante, P; Martelli, Ml; Trapasso, F; Chiariotti, L; Fusco, A; Iuliano, R
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis 1-gen-2004 Iuliano, R.; LE PERA, I.; Cristofaro, C.; Baudi, F.; Arturi, F; Pallante, P. L.; Martelli, M. L.; Trapasso, F.; Chiariotti, L.; Fusco, A.
The v-erbA oncogene selectively inhibits iodide uptake in rat thyroid cells 1-gen-1996 Trapasso, F; Martelli, Ml; Battaglia, C; Angotti, E; Mele, E; Stella, A; Samarut, J; Avvedimento, Ve; Fusco, A
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas 1-gen-2005 Fedele, M; Pentimalli, F; Baldassarre, G; Battista, S; KLEIN-SZANTO, Aj; Kenyon, L; Visone, R; DE MARTINO, I; Ciarmiello, A; Arra, C; Viglietto, G; Croce, Cm; Fusco, A
Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts 1-gen-1998 Fedele, M; Berlingieri, Mt; Scala, S; Chiariotti, L; Viglietto, G; Rippel, V; Bullerdiek, J; Santoro, M; Fusco, A.
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14 1-gen-1993 Maglione, D; Guerriero, V; Viglietto, G; Ferraro, Mg; Aprelikova, O; Alitalo, K; DEL VECCHIO, S; Lei, Kj; Chou, Jy; Persico, Mg
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