The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
2007-01-01 Caraglia, M; Marra, M; Viscomi, C; D'Alessandro, Am; Budillon, A; Meo, G; Arra, C; Barbieri, A; Rapp, Ur; Baldi, A; Tassone, P; Venuta, S; Abbruzzese, A; Tagliaferri, P
Hereditary nonpolyposis colon cancer results from heritable defects in the MLH1, MSH2, PMS1 and PMS2 genes, which encode proteins involved in the mismatch repair process. In this work we report the identification of two novel germline mutations in the MLH1 gene from two unrelated HNPCC families. The two affected families do not fulfill the Amsterdam criteria. In family 1 we found a missense S93G mutation, which lies in a MLH1 domain critical for its MMR functions. In family 2 we found a two nucleotide insertion (AG) in position 523 from the AUG which determines an early stop codon at position 606 (codon 203). In both families the mutant alleles cosegregate with the cancer phenotype.
1998-01-01 Quaresima, B1; Grandinetti, C; Baudi, F; Tassone, P; Barbieri, V; Conforti, S; Avvedimento, Ev; Costanzo, F; Venuta, S
Identification of polymorphic variants associated with erlotinib-related skin toxicity in advanced non-small cell lung cancer patients by DMET microarray analysis
2016-01-01 Arbitrio, M; Di Martino, Mt; Barbieri, V; Agapito, G; Botta, C; Iuliano, E; Scionti, F; Altomare, E; Codispoti, S; Conforti, S; Tassone, P; Tagliaferri, P; Cannataro, M; Guzzi, P
Profili problematici dell’esecuzione delle sentenze della Corte di giustizia di condanna degli Stati membri ex art. 260 TFUE, in Il Diritto dell'Unione Europea, 2015, p. 427-450.
2015-01-01 Mori, P
The sodium-phosphate co-transporter SLC34A2, and pulmonary alveolar microlithiasis: presentation of an inbred family and a novel truncating mutation in exon 3
2015-01-01 Vismara, Mf; Colao, E; Fabiani, F; Bombardiere, F; Tamburrini, O; Alessio, C; Manti, F; Pelaia, G; Romeo, P; Iuliano, R; Perrotti, N.
Neural versus pneumatic control of pressure support in patients with chronic obstructive pulmonary diseases at different levels of positive end expiratory pressure: a physiological study
2015-01-01 Liu, Ling; Xia, Feiping; Yang, Yi; Navalesi, Paolo; Beck, Jennifer; Sinderby, Christer; Qiu, Haibo; Longhini, F
Communication to the Editor
2002-01-01 Grembiale, Rd; Pelaia, G
Turbo-Proton Echo Planar Spectroscopic Imaging (t-PEPSI) MR technique in the detection of diffuse axonal damage in brain injury. Comparison with Gradient-Recalled Echo (GRE) sequence
2005-01-01 Giugni, E; Sabatini, U; Hagberg, Ge; Formisano, R; Castriota-Scanderbeg, A
A case of Hughes-Stovin syndrome associated with Budd-Chiari syndrome
2002-01-01 Grembiale, Rd; Calderazzo, M; Pelaia, G; Gallelli, A; Roccia, F; Vero, G; Naty, S; Maselli, R
Application of proteomics and peptidomics to COPD
2014-01-01 Pelaia, G; Terracciano, R; Vatrella, A; Gallelli, L; Busceti, Mt; Calabrese, C; Stellato, C; Savino, R; Maselli, R
CUTANEOUS MANIFESTATIONS IN PATIENTS WITH CHRONIC RENAL FAILURE ON HEMODIALYSIS
2014-01-01 Specchio, F.; Carboni, I.; Chimenti, S.; Tamburi, F.; Nistico', S
Bovine Papillomavirus Type 2 (BPV-2) E5 Oncoprotein Binds to the Subunit D of the V-1-ATPase Proton Pump in Naturally Occurring Urothelial Tumors of the Urinary Bladder of Cattle
2014-01-01 Roperto, Sante; Russo, Valeria; Borzacchiello, Giuseppe; Urraro, Chiara; Luca, Roberta; Esposito, Iolanda; Riccardi Marita, Georgia; Raso, Cinzia; Gaspari, M; Ceccarelli Dora, Maria; Galasso, Rocco; Roperto, Franco
Prevalence and pattern of antibiotic resistance of Campylobacter spp. in poultry meat in Southern Italy
2013-01-01 Nobile, Cga; Costantino, R; Bianco, A; Pileggi, C; Pavia, M
Healthcare workers and prevention of hepatitis C virus transmission: exploring knowledge, attitudes and evidence-based practices in hemodialysis units in Italy
2013-01-01 Bianco, A; Bova, F; Nobile, Cga; Pileggi, C; Pavia, M; and the Collaborative Working, Group.
The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance
2001-01-01 Baroni, Mg; Arca, M; Sentinelli, F; Buzzetti, R; Capici, F; Lovari, S; Vitale, M; Romeo, S; Di Mario, U
Complete clinical remission and disappearance of liver metastases after treatment with somatostatin analogue in a 40-year-old woman with a malignant insulinoma positive for somatostatin receptors type 2.
2006-01-01 Romeo, S; Milione, M; Gatti, A; Fallarino, M; Corleto, V; Morano, S; Baroni, Mg
The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; treatment with a PPARγ agonist restores normal cell signalling and differentiation
2006-01-01 Sentinelli, F; Filippi, E; Cavallo, Mg; Romeo, S; Fanelli, M; Baroni, Mg
BEHAVIORAL AND ELECTROCORTICAL EFFECTS AFTER INJECTION OF 2 ORNITHINE DECARBOXYLASE INHIBITORS INTO SEVERAL AREAS OF THE BRAIN IN THE RAT
1989-01-01 DE SARRO, G; Ascioti, C; Audino, Mg; Libri, V; Desarro, A; Nistico, G
Differences in the availability of new anti-cancer drugs for Italian patients treated in different regions. Results of analysis conducted by the Italian Society of Medical Oncology (AIOM)
2010-01-01 Gori, S; Di Maio, M; Pinto, C; Alabiso, O; Baldini, E; Berette, Gd; Caffo, O; Caroti, C; Crino, L; De Laurentiis, M; Dinota, A; Di Vito, F; Gebbia, V; Giustini, L; Graiff, C; Guida, M; Lelli, G; Lombardo, M; Muggiano, A; Puglisi, F; Romito, S; Salvagno, L; Tagliaferri, P; Terzoli, E; Venturini, M
La demanialità dei beni tra titolarità e funzione: verso un definitivo superamento delle categorie codicistiche?
2011-01-01 Saitta, F
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