Embryo-endometrium cross-talk represents the main limiting factor for a good implantation and pregnancy. At the time of implantation the interaction between blastocyst and endometrium, mediated by sex steroids hormones, immune cells and related soluble factors, induces significant modification in the superficial profile of extracellular matrix (ECM) proteins in both endometrium and blastocyst. More recently, it has been shown that also periostin (POSTN), a secreted ECM protein and a key element in metastatic processes plays an important role in the regulation
Periostin and implantation: a new biomarker of embryo-endometrial cross talk
Roberta Venturella;Barbara Quaresima;Fulvio Zullo;Costanzo F
2015-01-01
Abstract
Embryo-endometrium cross-talk represents the main limiting factor for a good implantation and pregnancy. At the time of implantation the interaction between blastocyst and endometrium, mediated by sex steroids hormones, immune cells and related soluble factors, induces significant modification in the superficial profile of extracellular matrix (ECM) proteins in both endometrium and blastocyst. More recently, it has been shown that also periostin (POSTN), a secreted ECM protein and a key element in metastatic processes plays an important role in the regulationFile in questo prodotto:
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