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EnglishMonotherapy with TPM was evaluated in an open-label study including 28 adult patients (17 men and 11 with women, aged 22 to 82 years) with recently diagnosed partial epilepsy. After a 2-24 months follow-up (mean 11.5 mths), 16 patients (57%) were seizure-free, 2 (7%) achieved a seizure reduction > 75%, 7 (25%) had a seizure reduction > 50%, and 3 patients (11%) had no improvement. Side effects including weight loss, paraesthesia and sedation were reported in 13 out of 28 patients (46%). Three out of 28 patients (11%) complained of sexual impotence. The results indicate that TPM is an effective and well tolerated drug when utilised in monotherapy.
| Titolo: | Topiramate monotherapy in adult patients with recently diagnosed partial epilepsy |
| Autori: | |
| Data di pubblicazione: | 2002 |
| Rivista: | |
| Handle: | http://hdl.handle.net/20.500.12317/20338 |
| Appare nelle tipologie: | 4.1 Contributo in Atti di convegno |
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http://hdl.handle.net/20.500.12317/20338
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