Advanced skin carcinoma, according to TNM classification, is as a lesion in stage III or IV (T3-T4, N0-N1, M0-M1) greater than 5 cm in greatest diameter (T3). It can infiltrate extradermal tissues (T4) or it can have local lymph node metastasis (N1) or distant metastasis (M1). In a large percentage of these patients, local relapses with deep infiltration, regional lymph node metastasis or distant metastases may be encountered. Current literature reports only few papers about advanced stage casistics. Therefore we reviewed our experience with elderly patients presenting skin carcinomas in advanced stage, to evaluate the incidence of this disorder among the whole number of skin carcinomas, the operability of those patients, the immediate clinical response to the surgical treatment and their follow-up. Materials and methods: From January 1st 2005 to June 30th 2009 we observed and treated 412 patients with skin carcinomas. Only patients with confirmed histopathological diagnosis of skin carcinoma were included in the study. The advanced stage of disease was established by physical examination and instrumental imaging exams. Results: The more frequent diagnoses were basal cell carcinomas, squamous cell carcinoma and porocarcinoma.
Treatment of advanced skin carcinoma in elderly people
GRECO M;
2010-01-01
Abstract
Advanced skin carcinoma, according to TNM classification, is as a lesion in stage III or IV (T3-T4, N0-N1, M0-M1) greater than 5 cm in greatest diameter (T3). It can infiltrate extradermal tissues (T4) or it can have local lymph node metastasis (N1) or distant metastasis (M1). In a large percentage of these patients, local relapses with deep infiltration, regional lymph node metastasis or distant metastases may be encountered. Current literature reports only few papers about advanced stage casistics. Therefore we reviewed our experience with elderly patients presenting skin carcinomas in advanced stage, to evaluate the incidence of this disorder among the whole number of skin carcinomas, the operability of those patients, the immediate clinical response to the surgical treatment and their follow-up. Materials and methods: From January 1st 2005 to June 30th 2009 we observed and treated 412 patients with skin carcinomas. Only patients with confirmed histopathological diagnosis of skin carcinoma were included in the study. The advanced stage of disease was established by physical examination and instrumental imaging exams. Results: The more frequent diagnoses were basal cell carcinomas, squamous cell carcinoma and porocarcinoma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
