Ultrasound energy at frequencies lower than 200 kHz has recently been used in the medical field to improve transdermal drug transport and to achieve a more suitable therapeutic approach. Low-frequency ultrasound energy was shown to be more effective than high-frequency ultrasound energy, so low-frequency ultrasound is attracting its share of attention in the medical field. In this paper, we take into consideration the most promising applications of low-frequency ultrasound with emphasis on transducer technology and measurements. In particular, a piezopolymer transducer is proposed, originally aimed at emulating the biosonar of bats, which has a low acoustic impedance in correspondence to biological tissue. The transducer is light, small, and inexpensive and could be used for medical applications, a possibility of which is a potential device for improving the cutaneous passage of drug compounds.

Ultrasound energy at frequencies lower than 200 kHzhas recently been used in the medical field to improve transdermaldrug transport and to achieve a more suitable therapeutic approach.Low-frequency ultrasound energy was shown to be moreeffective than high-frequency ultrasound energy, so low-frequencyultrasound is attracting its share of attention in the medical field.In this paper, we take into consideration the most promising applicationsof low-frequency ultrasound with emphasis on transducertechnology and measurements. In particular, a piezopolymertransducer is proposed, originally aimed at emulating the biosonarof bats, which has a low acoustic impedance in correspondence tobiological tissue. The transducer is light, small, and inexpensiveand could be used for medical applications, a possibility of whichis a potential device for improving the cutaneous passage of drugcompounds.

Low-Frequency Ultrasound in Medicine: An In Vivo Evaluation

Fiorillo A;Paolino D;Pullano S
2012-01-01

Abstract

Ultrasound energy at frequencies lower than 200 kHz has recently been used in the medical field to improve transdermal drug transport and to achieve a more suitable therapeutic approach. Low-frequency ultrasound energy was shown to be more effective than high-frequency ultrasound energy, so low-frequency ultrasound is attracting its share of attention in the medical field. In this paper, we take into consideration the most promising applications of low-frequency ultrasound with emphasis on transducer technology and measurements. In particular, a piezopolymer transducer is proposed, originally aimed at emulating the biosonar of bats, which has a low acoustic impedance in correspondence to biological tissue. The transducer is light, small, and inexpensive and could be used for medical applications, a possibility of which is a potential device for improving the cutaneous passage of drug compounds.
2012
Ultrasound energy at frequencies lower than 200 kHzhas recently been used in the medical field to improve transdermaldrug transport and to achieve a more suitable therapeutic approach.Low-frequency ultrasound energy was shown to be moreeffective than high-frequency ultrasound energy, so low-frequencyultrasound is attracting its share of attention in the medical field.In this paper, we take into consideration the most promising applicationsof low-frequency ultrasound with emphasis on transducertechnology and measurements. In particular, a piezopolymertransducer is proposed, originally aimed at emulating the biosonarof bats, which has a low acoustic impedance in correspondence tobiological tissue. The transducer is light, small, and inexpensiveand could be used for medical applications, a possibility of whichis a potential device for improving the cutaneous passage of drugcompounds.
Cavitation,; Drug delivery; Ultrasound transducer
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12317/3641
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