In this paper, a Q-tube equipment is proposed as a valid alternative to monomode MW technology to synthesize in a simple and economic way a library of dihydropyrimidine derivatives performing the Biginelli reaction in solvent-free conditions under pressure and with the catalysis of a very mild and environmentally benign Lewis acid consisting of erbium trichloride hexahydrate.

Facile Ecofriendly Synthesis of Monastrol and Its Structural Isomers via Biginelli Reaction

Nardi M;Procopio A;Oliverio M
2014-01-01

Abstract

In this paper, a Q-tube equipment is proposed as a valid alternative to monomode MW technology to synthesize in a simple and economic way a library of dihydropyrimidine derivatives performing the Biginelli reaction in solvent-free conditions under pressure and with the catalysis of a very mild and environmentally benign Lewis acid consisting of erbium trichloride hexahydrate.
2014
Monastrol; Biginelli reaction; Q-tube reactor
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12317/5845
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