The complete set of the 4-'aza analogues of 2',3'-dideoxynucleosides was synthesized by cycloaddition of N-tetrahydropiranyl or N-trityl methylene nitrones on suitably protected vinyl nucleobases. The convertible nucleoside approach was used in the preparation of cytosine and 5-methyl cytosine analogues.
Synthesis of isoxazolidino analogues of 2',3'-dideoxynucleosides
De Nino A.;Procopio A.;Sindona G.
1999-01-01
Abstract
The complete set of the 4-'aza analogues of 2',3'-dideoxynucleosides was synthesized by cycloaddition of N-tetrahydropiranyl or N-trityl methylene nitrones on suitably protected vinyl nucleobases. The convertible nucleoside approach was used in the preparation of cytosine and 5-methyl cytosine analogues.File in questo prodotto:
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