Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.
Atrial myxomas arise from multipotent cardiac stem cells
Scalise, M.;Marino, F.;Vicinanza, C.;Cianflone, E.;Mancuso, T.;Aquila, I.;Salerno, L.;Agosti, V.;De Angelis, A.;Urbanek, K.;Veltri, P.;Paolino, D.;Mastroroberto, Pasquale;De Feo, Marisa;Viglietto, G.;Weisz, A.;Torella, D.
2020-01-01
Abstract
Cardiac myxomas usually develop in the atria and consist of an acid-mucopolysaccharide-rich myxoid matrix with polygonal stromal cells scattered throughout. These human benign tumours are a valuable research model because of the rarity of cardiac tumours, their clinical presentation and uncertain origin. Here, we assessed whether multipotent cardiac stem/progenitor cells (CSCs) give rise to atrial myxoma tissue.File in questo prodotto:
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