We studied 19 patients (pts) as compassionate case, with an age between 17 and 44 years (mean 29 ys), with a duration of epilepsy between 5 and 30 years, all with diagnosis of drug-resistant epilepsy. The pts were 13 with partial epilepsy, 3 with Lennox-Gastaut syndrome, 2 with multifocal partial epilepsy with non progressive brain damage and 1 with Lafora disease. All pts have been followed for a period between 12 and 40 months. In 2 (10.5%) pts we observed a complete disappearance of the seizures, and in 3 (15.8%) a greater than 50% reduction in total seizure number. Tolerance to Vigabatrin was good and no patient was withdrawn because of side effects.
Follow-up of 19 patients with drug-resistant epilepsy treated with Vigabatrin
Aguglia U.;
1991-01-01
Abstract
We studied 19 patients (pts) as compassionate case, with an age between 17 and 44 years (mean 29 ys), with a duration of epilepsy between 5 and 30 years, all with diagnosis of drug-resistant epilepsy. The pts were 13 with partial epilepsy, 3 with Lennox-Gastaut syndrome, 2 with multifocal partial epilepsy with non progressive brain damage and 1 with Lafora disease. All pts have been followed for a period between 12 and 40 months. In 2 (10.5%) pts we observed a complete disappearance of the seizures, and in 3 (15.8%) a greater than 50% reduction in total seizure number. Tolerance to Vigabatrin was good and no patient was withdrawn because of side effects.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
