Selective antagonists of Endothelin-1 receptors (ERA) have been tested in diabetic and nondiabetic chronic kidney disease (CKD). The SONAR trial (Study Of diabetic Nephropathy with AtRasentan) was the first randomized, phase 3, study assessing the long-term effect of ERA on CKD progression.

Selective endothelin A receptor antagonism in patients with proteinuric chronic kidney disease

Provenzano, Michele;Andreucci, Michele;Serra, Raffaele;
2021-01-01

Abstract

Selective antagonists of Endothelin-1 receptors (ERA) have been tested in diabetic and nondiabetic chronic kidney disease (CKD). The SONAR trial (Study Of diabetic Nephropathy with AtRasentan) was the first randomized, phase 3, study assessing the long-term effect of ERA on CKD progression.
2021
Cardiovascular risk
Chronic Kidney Disease
ERA
End-Stage-Kidney-Disease
endothelin
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12317/65217
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