Two new localizations of Solitary Fibrous Tumour in Italian population: parothid gland and oral cavity. Review of literature.

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm, first described by Klemperer and Rabin1 in 1931 in the visceral pleura. Recently, the SFT has been reported in many other extrapleural sites, including the head and neck as an orbit tumor,2,3 infratemporal fossa,4,5 parapharyngeal space,6-8 upper airways, nose,9-11 mediastinum,12 salivary and thyroid glands, and oral cavity.13-25 The finding of SFT in the salivary glands and oral cavity is very unusual. Diagnosis is difficult because SFTs have a wide morphologically different range. Only immunohistochemical examination (vimentin, CD34, and blc-2) is useful for diagnosis. In 5% to 23% of pleural SFT cases, there is a malignant evolution. Extrathoracic SFTs (like intraoral SFTs) have an excellent prognosis associated with their benign clinical behavior. We describe 2 new rare cases of SFT: an SFT of the right parotid gland in a younger patient and an SFT in the oral cavity in the other patient. Both patients underwent surgery and have remained free of disease (for 5 years in the first patient and for 2 years in the second)