Background: Aging is the product of interaction between multiple bio-psycho-social factors. The progressive decline of cognitive functions and the reduction of motor and functional performance represent outcomes commonly associated with aging. The aim of this cross-sectional study was to investigate the association of cognitive reserve with cognitive, functional and motoric outcomes in a sample of elderly outpatients. Methods: Seventy outpatients aged ≥65 were consecutively evaluated. Patients unable to undergo the execution of required tasks due to severe cognitive-functional impairment or severe sensory deficits were excluded. MMSE, Cognitive Reserve Index Questionnaire and Short Intelligence Test were administered. Handgrip and gait speed were measured; a Frailty Index was also calculated for each patient. Findings: Cognitive reserve was significantly correlated with MMSE (r = 0.529, p <0.05), handgrip (r = 0.471, p <0.05) and gait speed (r = 0.278, p <0, 05). Furthermore, cognitive reserve was inversely correlated with the FI (r = -0.554, p <0.05). Significant correlations were found between TIB and MMSE (r = 0.310, p <0.05) and between TIB and CRIq (r = 0.531, p <0.05). The TIB was inversely correlated with the FI (r = -0,269, p <0.05). Discussion: Patients with higher cognitive reserve and higher pre-morbid IQ presented better overall cognitive functioning, better functional performances and lower degree of frailty. The assessment of cognitive reserve and pre-morbid IQ in elderly may offer the opportunity to track possible trajectories of aging which are related to cognitive status as well as to functional outcomes and frailty.
Impact of Cognitive Reserve in Elderly Outpatients with Reduced Cognitive-Motor Functions
Lenzo V.;Barberis N.;
2019-01-01
Abstract
Background: Aging is the product of interaction between multiple bio-psycho-social factors. The progressive decline of cognitive functions and the reduction of motor and functional performance represent outcomes commonly associated with aging. The aim of this cross-sectional study was to investigate the association of cognitive reserve with cognitive, functional and motoric outcomes in a sample of elderly outpatients. Methods: Seventy outpatients aged ≥65 were consecutively evaluated. Patients unable to undergo the execution of required tasks due to severe cognitive-functional impairment or severe sensory deficits were excluded. MMSE, Cognitive Reserve Index Questionnaire and Short Intelligence Test were administered. Handgrip and gait speed were measured; a Frailty Index was also calculated for each patient. Findings: Cognitive reserve was significantly correlated with MMSE (r = 0.529, p <0.05), handgrip (r = 0.471, p <0.05) and gait speed (r = 0.278, p <0, 05). Furthermore, cognitive reserve was inversely correlated with the FI (r = -0.554, p <0.05). Significant correlations were found between TIB and MMSE (r = 0.310, p <0.05) and between TIB and CRIq (r = 0.531, p <0.05). The TIB was inversely correlated with the FI (r = -0,269, p <0.05). Discussion: Patients with higher cognitive reserve and higher pre-morbid IQ presented better overall cognitive functioning, better functional performances and lower degree of frailty. The assessment of cognitive reserve and pre-morbid IQ in elderly may offer the opportunity to track possible trajectories of aging which are related to cognitive status as well as to functional outcomes and frailty.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
