Chronic sclerosing sialadenitis of submandibular gland. A case report with literature review

Aim: This study aims to demonstrate how surgery is fundamental in the case of the Kuttner Tumour. In fact, the few data in the literature could lead to erroneous diagnoses with subsequent underestimation of the dis- ease. Material of the study: A systematic review of the literature on chronic sclerosing sialadenitis, also known as Kuttner Tumor, was carried out. All cases published from 1976 to the present have been examined. Results: Kuttner Tumour is an immune-mediated localized fibro inflam- matory condition that often mimics other pathological processes, such as malignant neoplasia. Discussion: The variables analyzed in each article included in this review were the age and gender of the patients, the location of the disease, the type of study; clinical presentation, instrumental tests performed, presence of IgG4, surgery performed and the evolution of patients after treatment were also assessed. Diagnosis should be based on clinical, serological, and pathological findings, but in a small percentage of cases (just as in the case presented) the cytological data provided by FNAB and serum IgG4 levels do not allow a diagnosis. Conclusions: Our experience shows that only surgery with subsequent his- tological examination allows to correctly diagnose the disease.