Subjects with elevated 1 h post-load glucose concentrations (1hPG) exhibit increased risk of non-alcoholic fatty liver disease (NAFLD) and duodenal sodium/glucose co-transporter 1 (SGLT-1) levels. Herein, we evaluate whether higher SGLT-1 duodenal levels are associated with NAFLD and increased risk of advance liver fibrosis.

Augmented duodenal levels of sodium/glucose co-transporter 1 are associated with higher risk of nonalcoholic fatty liver disease and noninvasive index of liver fibrosis

Teresa Vanessa Fiorentino;Francesca De Vito;Evelina Suraci;Federica Catalano;Francesco Andreozzi;Marta Letizia Hribal;Francesco Luzza;Giorgio Sesti
2022-01-01

Abstract

Subjects with elevated 1 h post-load glucose concentrations (1hPG) exhibit increased risk of non-alcoholic fatty liver disease (NAFLD) and duodenal sodium/glucose co-transporter 1 (SGLT-1) levels. Herein, we evaluate whether higher SGLT-1 duodenal levels are associated with NAFLD and increased risk of advance liver fibrosis.
2022
1h post-load hyperglycemia
Duodenal SGLT-1
ER stress
Liver fibrosis
NAFLD
Sodium/glucose co-transporter 1
Glucose
Humans
Liver Cirrhosis
Sodium
Triglycerides
Non-alcoholic Fatty Liver Disease
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12317/81130
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