Background: Pharmacotherapy and immunotherapy are the main treatments for allergic diseases to inhalants. Objective: This study investigates whether to repeat short cycles of immunotherapy after 3 or 5 years the from interruption of the first therapeutic cycle, lasting 3-4 years, to maintain immune memory in individuals subjected to IST. Methods and results: We have compared two groups, one of 452 patients who, after the first treatment for 3-4 years of IST, performed a cycle of four months after three and 10 years from the suspension, and a second group of 126 individuals who have performed only the IST treatment for 3-4 years. The best results were obtained in the first group. Conclusions: These results are due to the immune system's plasticity, a very important concept in clinical practice.
Plasticity of immune system vs. memory therapy IST
Tammaro, A;
2017-01-01
Abstract
Background: Pharmacotherapy and immunotherapy are the main treatments for allergic diseases to inhalants. Objective: This study investigates whether to repeat short cycles of immunotherapy after 3 or 5 years the from interruption of the first therapeutic cycle, lasting 3-4 years, to maintain immune memory in individuals subjected to IST. Methods and results: We have compared two groups, one of 452 patients who, after the first treatment for 3-4 years of IST, performed a cycle of four months after three and 10 years from the suspension, and a second group of 126 individuals who have performed only the IST treatment for 3-4 years. The best results were obtained in the first group. Conclusions: These results are due to the immune system's plasticity, a very important concept in clinical practice.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
