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In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 1-gen-2014 Amato, R; D'Antona, L; Costa, G; Talarico, C; Gigliotti, F; Trapasso, F; Schenone, S; Musumeci, F; Botta, L; Ortuso, F; Perrotti, N; Alcaro, S; Artese, A; Bianco, C
New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors 1-gen-2014 Malet, I; Gimferrer Arriaga, L; Costa, G; Parrotta, L; Alcaro, S; Delelis, O; Tmeizeh, A; Katlama, C; Valantin, Ma; Ceccherini-Silberstein, F; Calvez, V; Marcelin, Ag; Artese, A
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? 1-gen-2014 Parrotta, L; Ortuso, F; Moraca, F; Rocca, R; Costa, G; Artese, A.; Alcaro, S
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 1-gen-2015 Surdo, M; Alteri, C; Puertas, Mc; Saccomandi, P; Parrotta, L; Swenson, L; Chapman, D; Costa, G; Balestra, E; Aquaro, S; Alcaro, S; Lewis, M; Clotet, B; Harrigan, R; Valdez, H; Svicher, V; Perno, Cf; Martinez-Picado, J; Ceccherini-Silberstein, F; Artese, A
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 1-gen-2015 D'Ascenzio, M; Chimenti, P; Gidaro, Mc; De Monte, C; De Vita, D; Granese, A; Scipione, L; Di Santo, R; Costa, G; Alcaro, S; Yáñez, M; Carradori, S
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 1-gen-2015 D'Antona, Lucia; Amato, Rosario; Talarico, Cristina; Ortuso, Francesco; Menniti, Miranda; Dattilo, Vincenzo; Iuliano, Rodolfo; Francesco, Gigliotti; Artese, Anna; Costa, Giosue'; Silvia, Schenone; Francesca, Musumeci; Claudia, Abbruzzese; Lorenzo, Botta; Trapasso, Francesco; Alcaro, Stefano; Paggi, Marco G.; Perrotti, N
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 1-gen-2015 De Monte, C; Bizzarri, B; Gidaro, Mc; Carradori, S; Mollica, A; Luisi, G; Granese, A; Alcaro, S; Costa, G; Basilico, N; Parapini, S; Scaltrito, Mm; Masia, C; Sisto, F
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 1-gen-2015 Gidaro, Mc; Alcaro, F; Carradori, S; Costa, G; Vullo, D; Supuran, Ct; Alcaro, S
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 1-gen-2015 Alteri, C; Surdo, M; Bellocchi, Mc; Saccomandi, P; Continenza, F; Armenia, D; Parrotta, L; Carioti, L; Costa, G; Fourati, S; Di Santo, F; Scutari, R; Barbaliscia, S; Fedele, V; Carta, S; Balestra, E; Alcaro, S; Marcelin, Ag; Calvez, V; Ceccherini-Silberstein, F; Perno, Cf; Svicher, V; Artese, A
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 1-gen-2015 Rocca, R; Moraca, F; Costa, G; Distinto, S; Maccioni, E; Ortuso, F; Parrotta, L; Alcaro, S; Artese, A
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 1-gen-2016 Pavia, G; Marascio, N; Romeo, I; Talarico, C; Costa, G; Zicca, E; Barreca, Gs; Postorino, Mc; Mazzitelli, M; Torti, C; Artese, A; Alcaro, S; Liberto, Mc; Focà, A.
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 1-gen-2016 Pavia, G; Marascio, N; Romeo, I; Talarico, C; Costa, G; Artese, A; Alcaro, S; Zicca, E; Barreca, Gs; Strazzulla, A; Torti, C; Liberto, Mc; Focà, A.
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 1-gen-2016 Doria, F; Nadai, M.; Costa, G; Sattin, G; Gallati, C; Bergamaschi, G; Moraca, F; Alcaro, S; Freccero, M; Richter, Sn
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 1-gen-2016 Carradori, S; Gidaro, Mc; Petzer, A; Costa, G; Guglielmi, P; Chimenti, P; Alcaro, S; Petzer, Jp
The HIV-1 reverse transcriptase polymorphism A98S improves the response to tenofovir disoproxil fumarate + emtricitabine-containing HAART both in vivo and in vitro 1-gen-2016 Alteri, C; Surdo, M; Maio, Di; Vc, ; Santo, Di; Costa, F; Parrotta, G; Romeo, L; Gori, I; Santoro, C; Fedele, Mm; Carta, V; Continenza, S; Pinnetti, F; Bellagamba, C; Liuzzi, R; Orchi, G; Latini, N; Bertoli, A; Girardi, A; E, ; Alcaro, S; Giuliani, M; Petrosillo, N; Andreoni, M; Antinori, A; Monforte, Ad; Ceccherini-Silberstein, F; Perno, Cf; Svicher, V; Artese, A
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 1-gen-2016 Rocca, R; Costa, G; Artese, A; Parrotta, L; Ortuso, F; Maccioni, E; Pinato, O; Greco, Ml; Sissi, C; Alcaro, S; Distinto, S; Moraca, F.
Exploring new chemical functionalities to improve aromatase inhibition of steroids 1-gen-2016 Varela, Cl; Amaral, C; Correia-da-Silva, G; Costa, Sc; Carvalho, Ra; Costa, G; Alcaro, S; Teixeira, Naa; Tavares-da-Silva, Ej; Roleira, Fmf
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 1-gen-2016 Gidaro, Mc; Astorino, C; Petzer, A; Carradori, S; Alcaro, F; Costa, G; Rafele, G; Russo, Fm; Petzer, Jp; Alcaro, S; Artese, A
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 1-gen-2016 Costa, G; Rocca, R; Moraca, F; Talarico, C; Romeo, I; Ortuso, F; Artese, A; Alcaro, S
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 1-gen-2016 Rocca, R; Costa, G; Artese, A; Parrotta, L; Ortuso, F; Maccioni, E; Pinato, O; Greco, Ml; Sissi, C; Alcaro, S; Distinto, S; Moraca, F; Alcaro, S; Artese, A
Mostrati risultati da 41 a 60 di 121
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