IRIS
SAVINO, Rocco
 Distribuzione geografica
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Continente #
NA - Nord America 1.771
AS - Asia 775
EU - Europa 625
SA - Sud America 15
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 5
AF - Africa 2
Totale 3.199
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Nazione #
US - Stati Uniti d'America 1.699
SG - Singapore 516
IT - Italia 354
CN - Cina 226
SE - Svezia 114
CA - Canada 71
GB - Regno Unito 64
DE - Germania 42
IN - India 16
BR - Brasile 9
CZ - Repubblica Ceca 9
ES - Italia 7
RO - Romania 7
EU - Europa 6
FR - Francia 6
AU - Australia 5
HK - Hong Kong 5
IR - Iran 4
NL - Olanda 4
AT - Austria 3
CL - Cile 3
RU - Federazione Russa 3
UA - Ucraina 3
IE - Irlanda 2
IL - Israele 2
JP - Giappone 2
TR - Turchia 2
ZA - Sudafrica 2
AR - Argentina 1
BG - Bulgaria 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
EE - Estonia 1
FI - Finlandia 1
HR - Croazia 1
MD - Moldavia 1
NO - Norvegia 1
OM - Oman 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
Totale 3.199
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Città #
Chandler 357
Singapore 153
Santa Clara 142
Milan 134
Princeton 134
Lawrence 130
Wilmington 79
Catanzaro 70
Ottawa 67
Ashburn 57
London 50
Chicago 43
Boardman 41
Des Moines 41
Shanghai 30
Troina 27
Guangzhou 23
Beijing 21
Norwalk 15
Seattle 14
Naples 13
New York 13
Florence 12
Wuhan 12
Falls Church 11
Pune 9
Redmond 9
Cicciano 8
Los Angeles 8
Olomouc 8
Rome 8
Shenzhen 7
Ann Arbor 6
Council Bluffs 6
Hanover 6
Jiaxing 5
Parenti 5
Redwood City 5
Girona 4
Hong Kong 4
Horia 4
Mountain View 4
Munich 4
Washington 4
West Jordan 4
Amsterdam 3
Curitiba 3
Palermo 3
Rui'an 3
Vibo Valentia 3
Andover 2
Assago 2
Atlanta 2
Campbelltown 2
Esslingen am Neckar 2
Ferrara 2
Foggia 2
Hangzhou 2
Nanjing 2
Nantong 2
Novokuznetsk 2
Padova 2
Rende 2
Squillace 2
The Dalles 2
Timisoara 2
Toronto 2
Verona 2
Wuxi 2
Xi'an 2
Zhenjiang 2
Zibo 2
Afragola 1
Aiello Calabro 1
Augusta 1
Aversa 1
Bengbu 1
Berlin 1
Brierley Hill 1
Campinas 1
Changsha 1
Chisinau 1
Clifton 1
Conselheiro Lafaiete 1
Cupertino 1
Dalian 1
Dongguan 1
Dongyang 1
Dourados 1
Dublin 1
Durban 1
Elk Grove Village 1
Fayetteville 1
Foshan 1
Frankfurt am Main 1
Fulham 1
Galway 1
Ginowan 1
Gioiosa Ionica 1
Handan 1
Totale 1.894
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Nome #
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-α and Haemophilus influenzae in human bronchial epithelial cells 58
An Analytical Method for Assessing Optimal Storage Conditions of Gingival Crevicular Fluid and Disclosing a Peptide Biomarker Signature of Gingivitis by MALDI-TOF MS 57
Application of proteomics and peptidomics to COPD 47
Asthma and COPD proteomics: Current approaches and future directions 46
An interleukin-6 antagonist modified for bone targeting preserves anti-myeloma biological activity 43
Biological mechanisms underlying the clinical effects of allergen-specific immunotherapy in asthmatic children 42
MALDI MS-Based Investigations Targeting SARS-CoV-2 41
Hexagonal Mesoporous Silica as a Rapid, Efficient and Versatile Tool for MALDI-TOF MS Sample Preparation in Clinical Peptidomics Analysis: A Pilot Study. 40
Objective and self-evaluation voice analysis after transoral laser cordectomy and radiotherapy in T1a-T1b glottic cancer 38
Mesopore-assisted Profiling of Human Synovial Fluid 37
Integrating peptidomic with lipidomic fingerprints by using mesoporous aluminosilicate and MALDI-TOF MS 37
Associazione di antagonisti di IL-6 e farmaci anti-proliferativi (depositato il 10.3.2005 n. RM2005A000103) 37
A METHODOLOGY FOR SELECTING SUPERAGONISTS, ANTAGONISTS AND SUPERANTAGONISTS OF HORMONES WHOSE RECEPTOR COMPLEX INCLUDES GP 130 37
A fast and sensitive colorimetric assay for IL-6 in hepatoma cells based on the production of a secreted form of alkaline phsphatase (SEAP) 36
ADENOVIRAL VECTORS ENCODING ERYTHROPOIETIN AND THEIR USE IN GENE THERAPY 36
TLR4 triggered complex inflammation in human pancreatic islets 35
An improved helper-dependent adenoviral vector allows persistent gene expression after i.m. delivery and overcomes pre-existing immunity to adenovirus 35
Rapid detection and identification of antimicrobial peptide fingerprints of nasal fluid by mesoporous silica particles and MALDI-TOF/TOF mass spectrometry: from the analytical approach to the diagnostic applicability in precision medicine 35
Biochemical modification of an Interleukin-6 antagonist to target myeloma cells in the bone marrow microenvironment 35
A rapid and reproducible standardized procedure for MALDI-TOF profiling of gingival crevicular fluid 35
Characteristics and clinical implications of the pharmacokinetic profile of ibuprofen in patients with knee osteoarthritis 35
Peptidome profiling of induced sputum by mesoporous silica beads and MALDI-TOF MS for biomarker discovery of Asthma and COPD 34
The molecular design of human IL-6 receptor antagonists 33
A rapid differential display analysis of nasal swab fingerprints to distinguish allergic from non-allergic rhinitis subjects by mesoporous silica particles and MALDI-TOF mass spectrometry 33
Two distinct and independent sites on IL-6 trigger gp130 dimer formation and signalling 32
Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung 32
The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial 32
Association between low bone mineral density and increased α-defensin in salivary fluid among postmenopausal women 31
Influence of storage conditions on MALDI-TOF MS profiling of gingival crevicular fluid: Implications on the role of S100A8 and S100A9 for clinical and proteomic based diagnostic investigations 31
An alternative approach for the identification of potential prostate cancer biomarkers 31
Biologics in severe asthma 31
Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non small lung cancer cells. 30
Generation of IL-6 antagonists by substituting residues in helix A 30
Application of MSB-MALDI-TOF-MS Technology to body fluids and Tissues peptidome profiling 30
PRERIBOSOMAL RNA PROCESSING IN XENOPUS-OOCYTES DOES NOT INCLUDE CLEAVAGE WITHIN THE EXTERNAL TRANSCRIBED SPACER AS AN EARLY STEP 29
Peptidome profiling of induced sputum by mesoporous silica beads and MALDI-TOF MS for non-invasive biomarker discovery of chronic inflammatory lung diseases 29
Assessment of pre-analytical and analytical variables affecting peptidome profiling of gingival crevicular fluid by MALDI-TOF mass spectrometry 29
Adenovirus-mediated gene transfer of a human IL-6 antagonist 29
Mesopore-assisted fingerprints of gingival crevicular fluid by MALDI-TOF mass spectrometry for monitoring inflammatory state in patients wearing fixed orthodontic appliance 29
Theophylline action on primary human bronchial epithelial cells under proinflammatory stimuli and steroidal drugs: a therapeutic rationale approach 29
Effect of a novel functional tomato sauce (OsteoCol) from vine-ripened tomatoes on serum lipids in individuals with common hypercholesterolemia: tomato sauce and hypercholesterolemia 29
REGULATION OF U3 SNRNA GENE-EXPRESSION 28
A paradigm shift for erythropoietin: no longer a specialized growth factor, but rather an all-purpose tissue-protective agent 28
Peptidomic analysis of induced sputum of asthmatic patients by MSB-MALDI-TOF-MS platform 28
Liposomal Delivery Improves the Growth Inhibitory and Apoptotic Activity of Low Doses of Gemcitabine in Multiple Myeloma Cancer Cells 28
Treatment with an adenoviral vector expressing the IL-6 receptor superantagonist sant7 compared with the treatment with the recombinant sant7 protein in MM cell lines 27
Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death 27
ANTAGONISTS OF HUMAN INTERLEUKIN-6 THAT ARE TOTALLY INCAPABLE OF BINDING GP 130, AND THEIR USE IN THE PREPARATION OF PHARMACEUTICAL COMPOUNDS 27
Simvastatin Action Is Not Related to HDAC2 Expression in Non-Small Cell Lung Cancer (NSCLC) 27
A PARADIGM SHIFT FOR ERYTHROPOIETIN: NO LONGER A SPECIALIZED GROWTH FACTOR, BUT RATHER THAN AN ALL-PURPOSE TISSUE-PROTECTIVE AGENT 27
Gingival Crevicular Fluid Peptidome Profiling in Healthy and in Periodontal Diseases. 27
Cell cycle regulation and induction of apoptosis by IL-6 variants on the multiple myeloma cell line XG-1 26
EXTRA-RIBOSOMAL SPACER SEQUENCES IN TRITURUS 26
Effects of Ambrisentan in a Patient Affected by Combined Pulmonary Fibrosis and Emphysema and by Severe Pulmonary Hypertension: Clinical, Functional, and Biomolecular Findings 26
A ROLE FOR U3 SMALL NUCLEAR RIBONUCLEOPROTEIN IN THE NUCLEOLUS 26
Identification of Novel Angiogenic Proteins in Multiple Myeloma Patient-Derived Endothelial Cells Using Proteome-Wide Analysis 26
ANTI-TUMOUR PHARMACEUTICAL COMPOSITIONS CAPABLE OF REDUCING DRUG RESISTANCE IN TUMOUR CELLS 26
Peptidome profiling of gingival crevicular fluid by MALDI-TOF/TOF mass spectrometry 26
Involvement of the Arg179 in the active site of human IL-6 26
Synergistic induction of growth arrest and apoptosis of human myeloma cells by the IL-6 super-antagonist Sant7 and Dexamethasone 25
Identification of residues critical for biological activity and receptor binding of human Interleukin-6 25
Liquid Cristalline Phases for the Ophthalmic Administration of Drug 25
Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide 25
Mapping the SARS-CoV-2–host protein–protein interactome by affinity purification mass spectrometry and proximity-dependent biotin labeling: A rational and straightforward route to discover host-directed anti-SARS-CoV-2 therapeutics 25
Omalizumab lowers asthma exacerbations, oral corticosteroid intake and blood eosinophils: Results of a 5-YEAR single-centre observational study 25
A rapid differential display analysis of nasal swab fingerprints to distinguish allergic from non-allergic rhinitis subjects by mesoporous silica particles and MALDI-TOF mass spectrometry 25
Revealing the Hidden Diagnostic Clues of Male Infertility from Human Seminal Plasma by Dispersive Solid Phase Extraction and MALDI-TOF MS 24
C3f is a potential tool for the staging of osteoarthritis 24
Monovalent phage display of human Interleukin (hIL)-6: selection of superbinder variants from a complex molecular repertoire in hIL-6 D-helix 24
Enhancing plasma peptide MALDI-TOF-MS profiling by mesoporous silica assisted crystallization 24
Mesoporous Beads: New Tools and Strategies in Body Fluids Proteomics 23
Combination of Interleukin-6 antagonists and antiproliferative drugs 23
MUTANT INTERLEUKIN 6 WITH IMPROVED BIOLOGICAL ACTIVITY OVER WILD INTERLEUKIN 6 23
ADENOVIRAL VECTORS FOR MUTANTS OF HUMAN INTERLEUKIN 6 (HIL-6) WITH HIL-6 ANTAGONIST ACTIVITY, PHARMACEUTICAL COMPOSITIONS THEREWITH AND THEIR USES 23
Effect of IL-6 variants in Multiple Myeloma:growth inhibition and induction of apoptosis in primary cells 22
Designing new agonists/antagonists of growth factor receptors- The rational design of a super-antagonist of the IL-6 receptor 22
Targeted proteomic approach in prostatic tissue: a panel of potential biomarkers for cancer detection 22
A mass spectrometry-based proteomic approach for the identification and quantification of potential biomarkers in prostate cancer. 22
USE OF MUTEINS OF WILD-TYPE CYTOKINES AS IMMUNOGENS 21
Designing new agonists/antagonists of growth factor receptors - rational design of a superantagonist of the IL-6 receptor 21
Interleukin-6 receptor superantagonist Sant7 inhibits TGF-beta-induced proliferation of human lung fibroblasts 21
Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells 21
Severe Eosinophilic Asthma: from the Pathogenic role of Interleukin-5 to the Therapeutic Action of Mepolizumab. 20
An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus 20
test di Valutazione di efficacia dei chemioterapici effettuato su tre distinte e complementari popolazioni cellulari derivate dalla massa tumorale solida 19
Definition of a complex binding site for gp130 in human interleukin-6 (IL-6) 19
MALDI-TOF MS ANALYSIS OF LOW-ABUNDANCE PEPTIDE ENRICHED FROM BODY FLUIDS BY MESOPOROUS SILICA BEADS 19
Liquid Crystalline Phases for the Ophthalmic Administration of Drug 18
Prolonged expression and effective readministration of erythropoietin delivered with a fully deleted adenoviral vector 18
Effects of simvastatin and rosuvastatin on RAS protein, matrix metalloproteinases and NF-kappa B in lung cancer and in normal pulmonary tissues 18
Functionalized Mesoporous silica beads for MALDI-TOF MS profiling of human plasma and urine 18
Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu in vivo model of human multiple myeloma 18
The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells 18
277 POSTER An interleukin-6 antagonist modified for bone targeting preserves anti-myeloma biological activity 17
Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets 17
Testosterone replacement therapy in insulin-sensitive hypogonadal men restores phosphatidylcholine levels by regulation of arachidonic acid metabolism 17
Synergistic induction of growth arrest and apoptosis of human myeloma 16
Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation 16
Simultaneous extraction and rapid visualization of peptidomic and lipidomic body fluids fingerprints using mesoporous aluminosilicate and MALDI-TOF MS. 16
In vivo neutralization of human IL-6 (hIL-6) achieved by immunization of hIL-6-transgenic mice with a hIL-6 receptor antagonist 16
Totale 2.792
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Categoria #
all - tutte 48.688
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.688
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202073 0 0 0 0 0 0 0 0 0 0 15 58
2020/2021191 17 3 1 3 7 2 3 5 136 8 0 6
2021/2022362 2 0 10 90 37 10 17 78 30 32 55 1
2022/20231.070 267 45 50 76 117 132 5 60 169 44 83 22
2023/2024420 63 59 54 22 26 100 4 24 5 7 11 45
2024/20251.154 216 140 77 87 122 167 5 29 183 125 3 0
Totale 3.299