Distribuzione geografica
Continente #
NA - Nord America 1.467
EU - Europa 531
AS - Asia 62
SA - Sud America 11
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 2
Totale 2.083
Nazione #
US - Stati Uniti d'America 1.405
IT - Italia 257
GB - Regno Unito 88
SE - Svezia 78
CA - Canada 55
UA - Ucraina 44
IN - India 32
DE - Germania 22
SG - Singapore 10
ES - Italia 8
CZ - Repubblica Ceca 7
FI - Finlandia 7
BR - Brasile 5
EU - Europa 5
FR - Francia 5
MX - Messico 5
IR - Iran 4
CN - Cina 3
DZ - Algeria 3
JP - Giappone 3
CL - Cile 2
CO - Colombia 2
DK - Danimarca 2
NL - Olanda 2
NZ - Nuova Zelanda 2
PH - Filippine 2
PT - Portogallo 2
RO - Romania 2
TR - Turchia 2
UY - Uruguay 2
VN - Vietnam 2
AL - Albania 1
AT - Austria 1
CH - Svizzera 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GR - Grecia 1
HK - Hong Kong 1
IE - Irlanda 1
IL - Israele 1
LV - Lettonia 1
MN - Mongolia 1
MY - Malesia 1
NG - Nigeria 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 2.083
Città #
Chandler 336
Lawrence 124
Princeton 124
Ashburn 111
London 72
Wilmington 70
Ottawa 53
Chicago 47
Des Moines 46
Catanzaro 38
Washington 19
Pune 15
Redmond 10
Rome 10
Norwalk 9
Singapore 9
Casoria 8
Los Angeles 8
Boardman 7
Helsinki 7
Olomouc 7
Crotone 6
Hanover 6
Messina 6
Cagliari 5
Luni 5
Redwood City 5
San Mateo 5
Heidesheim 4
Palermo 4
Seattle 4
Siena 4
Treviso 4
Avola 3
Bonn 3
Castrovillari 3
Catania 3
Cosenza 3
Giulianova 3
Latina 3
Padova 3
Pavia 3
San Cristóbal de La Laguna 3
Agrigento 2
Amaroni 2
Assago 2
Aversa 2
Bagnoli di Sopra 2
Bathinda 2
Bogotá 2
Ca Mau 2
Campobello di Licata 2
Caulonia 2
Cisterna di Latina 2
Essen 2
Fayetteville 2
Grottaglie 2
Islington 2
Jinan 2
Labico 2
Leeds 2
Milazzo 2
Montevideo 2
Naples 2
Napoli 2
Paris 2
Pescara 2
Phoenix 2
Pizzo 2
Pontedera 2
Porto 2
Ragusa 2
Reggio Calabria 2
San Jose 2
Santander 2
Sorrento 2
São Paulo 2
Valencia 2
Vigliano Biellese 2
Ahmedabad 1
Amsterdam 1
Auckland 1
Bhubaneswar 1
Caserta 1
Castellazzo Bormida 1
Central 1
Chennai 1
Christchurch 1
Clearwater 1
Comiso 1
Corigliano Calabro 1
Corozal 1
Country Club Hills 1
Cupertino 1
Dagupan City 1
Denver 1
Dublin 1
Fars 1
Ferrara 1
Frankfurt am Main 1
Totale 1.311
Nome #
GBPM: applicazione al docking molecolare 62
A Candidate multi-targeting approach to block the CD98hc oncoprotein 50
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 48
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 35
Chemioterapici antifungini 35
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 34
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 33
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 32
A Computational pathway toward the rational design of azinomycin analogues 31
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 31
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 30
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 30
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 29
Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures 29
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 29
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 29
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 28
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 28
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 28
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 28
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase 28
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 27
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 27
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 26
Characterization of the role of two additional HIV-1 reverse transcriptase mutations in the regulation of NNRTI resistance 26
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 26
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 25
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 24
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 24
Metodi computazionali e nutraceutica 24
Characterization and Structural Analysis of Novel Mutations in HIV-1 Reverse Transcriptase Involved in the Regulation of Resistance to Non-Nucleoside Inhibitors 24
Computer-based techniques for lead identification and optimization II: Advanced search methods 24
CoMFA studies of non covalent monoamine oxidase inhibitors 23
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 23
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 23
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 22
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 22
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 22
Conformational analysis of bioactive conformations in the drug discovery process 21
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 21
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 21
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 21
Computational analysis of HIV-1 reverse transcriptase complexes 21
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 20
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 20
Computational study on DNA G-quadruplex binding compounds 20
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 20
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 20
Characterization and structural analysis of HIV-1 integrase conservation 20
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 20
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 19
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 19
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 19
Identification of new G-quadruplex binders by combined virtual screening approaches. 19
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 19
Computational approaches for discovery and optimization of G-quadruplex binders 18
High-throughput lipophilicity screening of opioid-like analgesics: validation of computational methods by means of RP-HPLC analysis 17
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 17
Docking e virtual screening su composti naturali: esempi su quercitina e cucurbitacina 15
Hit identification of novel DNA-quadruplex ligands 15
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 15
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 15
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 14
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation 14
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 14
Docking studies of Lopinavir, Atazanavir and Darunavir binding modes to HIV-1 protease mutants 14
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 14
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 14
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 14
null 14
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 14
New Resistance Mutations to Nucleoside Reverse Transcriptase Inhibitors at Codon 184 of HIV-1 Reverse Transcriptase (M184L and M184T). 14
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 13
TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma 12
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 12
Composti per il G-quadruplex a struttura naftilimmidica 12
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 12
Computer-based techniques for lead identification and optimization i: Basics 12
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 11
Indagine statistica sulla diffusione delle tecnologie computazionali avanzate per la progettazione dei nuovi farmaci 11
Rational drug design of DNA cross-linking agents 11
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 10
Rational Design, Synthesis, Biophysical and Antiproliferative Evaluation of Fluorenone Derivatives with DNA G-Quadruplex Binding Properties 10
Molecular interaction fields in drug discovery: recent advances and future perspectives 10
Molecular models of HIV-1 targets/drugs 9
Studio computazionale su modelli PDB di HIV-1 9
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 9
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 8
State-of-the-art and dissemination of computational tools for drug-design purposes: a survey among Italian academics and industrial institutions 8
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 8
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 8
Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors 7
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 7
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 7
Rational drug design of DNA G-quadruplex binders using in silico approaches 7
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 7
Rational drug design of DNA G-quadruplex binders using structure-based computational approaches. 7
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 7
Real-life 3D therapy failure: analysis of NS5A 93H RAS plus 108K polymorphism in complex with ombitasvir by molecular modeling 7
Totale 1.974
Categoria #
all - tutte 29.539
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.539

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020151 0 0 0 4 11 3 14 11 15 11 22 60
2020/2021165 7 3 20 20 27 20 23 4 16 13 8 4
2021/2022331 4 2 10 64 23 6 14 80 22 33 69 4
2022/20231.003 253 48 46 72 111 72 9 70 156 59 83 24
2023/2024507 72 57 46 31 33 152 12 45 4 21 16 18
Totale 2.157