IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 1.949
AS - Asia 958
EU - Europa 948
SA - Sud America 98
AF - Africa 22
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 3.982
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Nazione #
US - Stati Uniti d'America 1.887
SG - Singapore 537
IT - Italia 466
CN - Cina 285
DE - Germania 129
GB - Regno Unito 115
BR - Brasile 85
SE - Svezia 64
CA - Canada 50
FI - Finlandia 46
UA - Ucraina 45
IN - India 39
HK - Hong Kong 25
JP - Giappone 21
ES - Italia 14
EE - Estonia 12
MX - Messico 9
ZA - Sudafrica 9
NL - Olanda 8
VN - Vietnam 8
CZ - Repubblica Ceca 7
FR - Francia 7
PL - Polonia 7
RU - Federazione Russa 6
DZ - Algeria 5
IQ - Iraq 5
IR - Iran 5
TR - Turchia 5
SA - Arabia Saudita 4
TN - Tunisia 4
BD - Bangladesh 3
CL - Cile 3
EU - Europa 3
ID - Indonesia 3
KR - Corea 3
LT - Lituania 3
PK - Pakistan 3
RO - Romania 3
TW - Taiwan 3
UY - Uruguay 3
AL - Albania 2
AT - Austria 2
CH - Svizzera 2
CO - Colombia 2
DK - Danimarca 2
EG - Egitto 2
IE - Irlanda 2
IL - Israele 2
NZ - Nuova Zelanda 2
PE - Perù 2
PT - Portogallo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AU - Australia 1
BO - Bolivia 1
CU - Cuba 1
EC - Ecuador 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
KE - Kenya 1
KG - Kirghizistan 1
LV - Lettonia 1
MY - Malesia 1
NG - Nigeria 1
PH - Filippine 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 3.982
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Città #
Chandler 295
Singapore 249
Santa Clara 136
Ashburn 132
Hefei 132
Dallas 125
Milan 108
Lawrence 99
Princeton 99
Munich 98
London 84
Chicago 70
Wilmington 61
Catanzaro 42
Ottawa 35
Los Angeles 33
Turku 31
Des Moines 30
Hong Kong 23
Tokyo 18
Brooklyn 17
San Nicola Manfredi 16
Rome 15
Shanghai 15
Palermo 14
Helsinki 13
Seattle 13
Boardman 12
New York 12
San Francisco 12
Washington 12
Hanover 11
Pune 11
Redmond 9
Aversa 8
Charlotte 8
Guangzhou 8
Norwalk 8
São Paulo 8
Beijing 7
Boston 7
Olomouc 7
The Dalles 7
Chennai 6
Crotone 6
Denver 6
Messina 6
Naples 6
San Mateo 6
Warsaw 6
Cagliari 5
Columbus 5
Council Bluffs 5
Dongyang 5
Florence 5
Johannesburg 5
Lamezia Terme 5
Napoli 5
San Jose 5
Shenzhen 5
Weihai 5
Assago 4
Casoria 4
Catania 4
Heidesheim 4
Phoenix 4
Redwood City 4
Santander 4
Siena 4
Stockholm 4
Toronto 4
Zhengzhou 4
Alassio 3
Ballabio 3
Brasília 3
Cosenza 3
Fontebuona 3
Genoa 3
Hanoi 3
Hyderabad 3
Jakarta 3
Jiaxing 3
Lahore 3
Las Vegas 3
Latina 3
Manchester 3
Mexico City 3
Montevideo 3
Montreal 3
Nola 3
Pachino 3
Pavia 3
Rio de Janeiro 3
Sellia Marina 3
Soverato Marina 3
Treviso 3
Vallefiorita 3
Vasto 3
Xi'an 3
Amaroni 2
Totale 2.374
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Nome #
GBPM: applicazione al docking molecolare 74
A Candidate multi-targeting approach to block the CD98hc oncoprotein 73
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 70
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 63
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 59
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 57
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 57
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 56
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 53
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 52
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 52
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 52
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 51
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 50
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 50
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 49
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 48
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 48
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 47
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 47
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 47
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 47
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 46
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 46
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 45
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 44
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 44
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 44
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 43
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 42
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 42
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 42
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 41
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 41
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 41
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 40
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 40
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 39
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 39
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 38
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 38
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 37
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 37
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 37
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 37
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 37
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 36
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 36
Exploring new chemical functionalities to improve aromatase inhibition of steroids 34
Computer-based techniques for lead identification and optimization i: Basics 34
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 34
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 34
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 33
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 33
Metodi computazionali e nutraceutica 33
Identification of new G-quadruplex binders by combined virtual screening approaches. 33
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 33
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 32
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 32
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 31
Identification of SET/EED dual binders as innovative PRC2 inhibitors 31
Computational study on DNA G-quadruplex binding compounds 31
The non-coding RNA landscape of plasma cell dyscrasias 31
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 31
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 30
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 29
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 29
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 29
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 29
Computational approaches for discovery and optimization of G-quadruplex binders 28
null 28
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 26
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 26
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 26
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 26
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 25
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity 25
Molecular interaction fields in drug discovery: recent advances and future perspectives 25
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 25
An overview on olfaction in the biological, analytical, computational, and machine learning fields 25
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 24
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 24
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease 24
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 24
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 24
New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation. 23
Docking comparativo per lo sviluppo di ligandi per il DNA G-Quadruplex 23
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 23
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 22
Computer-based techniques for lead identification and optimization I: Basics 22
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 22
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids 21
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 21
Rational drug design of DNA G-quadruplex binders using in silico approaches 21
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 21
Neurodegeneration: can metabolites from Eremurus persicus help? 20
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 20
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 20
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 20
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies. 20
Totale 3.644
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Categoria #
all - tutte 49.715
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.715
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021145 0 0 22 13 23 17 24 4 15 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.483 181 98 51 37 115 171 78 46 193 64 170 279
2025/2026578 192 357 29 0 0 0 0 0 0 0 0 0
Totale 4.105