IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 1.338
EU - Europa 491
AS - Asia 54
SA - Sud America 11
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 1.906
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Nazione #
US - Stati Uniti d'America 1.298
IT - Italia 241
GB - Regno Unito 90
SE - Svezia 60
UA - Ucraina 40
CA - Canada 38
DE - Germania 27
IN - India 22
CN - Cina 11
FI - Finlandia 7
SG - Singapore 6
BR - Brasile 5
ES - Italia 5
IR - Iran 5
CL - Cile 3
DZ - Algeria 3
EU - Europa 3
FR - Francia 3
JP - Giappone 3
RO - Romania 3
CH - Svizzera 2
DK - Danimarca 2
IE - Irlanda 2
KR - Corea 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
RU - Federazione Russa 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AU - Australia 1
CO - Colombia 1
EG - Egitto 1
GR - Grecia 1
HK - Hong Kong 1
IL - Israele 1
LV - Lettonia 1
MX - Messico 1
MY - Malesia 1
NG - Nigeria 1
NL - Olanda 1
PH - Filippine 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
Totale 1.906
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Città #
Chandler 295
Ashburn 105
Lawrence 99
Princeton 99
London 77
Chicago 61
Wilmington 61
Catanzaro 42
Ottawa 34
Des Moines 30
Washington 12
Hanover 11
Pune 11
Los Angeles 10
Redmond 9
Norwalk 8
Seattle 8
Helsinki 7
Rome 7
Crotone 6
Messina 6
San Mateo 6
Boardman 5
Cagliari 5
Napoli 5
Singapore 5
Casoria 4
Catania 4
Heidesheim 4
Redwood City 4
Siena 4
Zhengzhou 4
Alassio 3
Ballabio 3
Cosenza 3
Florence 3
Fontebuona 3
Genoa 3
Hyderabad 3
Latina 3
Pachino 3
Treviso 3
Amaroni 2
Aversa 2
Caulonia 2
Cisterna di Latina 2
Clearwater 2
Dublin 2
Essen 2
Gallipoli 2
Grottaglie 2
Jinan 2
Labico 2
Lamezia Terme 2
Leeds 2
Montevideo 2
Mountain View 2
Padova 2
Palermo 2
Pavia 2
Pizzo 2
Porto 2
Ragusa 2
Romainville 2
Rozzano 2
San Cristóbal de La Laguna 2
San Jose 2
Santander 2
Serra San Bruno 2
Toronto 2
Vigliano Biellese 2
Weimar 2
Yuseong-gu 2
Adelfia 1
Ahmedabad 1
Aiello Calabro 1
Auckland 1
Bhubaneswar 1
Bogotá 1
Bresso 1
Campi Salentina 1
Camponogara 1
Caserta 1
Castel Campagnano 1
Central 1
Chennai 1
Chiasso 1
Christchurch 1
Corigliano Calabro 1
Corozal 1
Country Club Hills 1
Cupertino 1
Dagupan City 1
Denver 1
Falkenstein 1
Ferrara 1
Florianópolis 1
Frankfurt am Main 1
Halifax 1
Horia 1
Totale 1.167
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Nome #
GBPM: applicazione al docking molecolare 60
A Candidate multi-targeting approach to block the CD98hc oncoprotein 50
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 48
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 40
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 35
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 34
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 32
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 31
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 30
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 30
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 30
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 29
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 29
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 29
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 28
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 28
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 28
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 28
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 28
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 28
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 28
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 27
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 26
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 25
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 25
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 25
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 24
Metodi computazionali e nutraceutica 24
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 24
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 24
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 23
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 22
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 22
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 22
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 22
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 22
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 21
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 21
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 21
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 21
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 21
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 20
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 20
Exploring new chemical functionalities to improve aromatase inhibition of steroids 20
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 20
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 20
Computational study on DNA G-quadruplex binding compounds 20
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 20
Identification of SET/EED dual binders as innovative PRC2 inhibitors 19
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 19
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 19
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 19
Identification of new G-quadruplex binders by combined virtual screening approaches. 19
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 19
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 19
Computational approaches for discovery and optimization of G-quadruplex binders 18
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 18
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 17
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 17
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 16
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 15
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 15
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 14
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 14
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 14
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 14
New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation. 13
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 13
The non-coding RNA landscape of plasma cell dyscrasias 13
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 13
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 12
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 12
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 12
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 12
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 12
Computer-based techniques for lead identification and optimization i: Basics 12
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 11
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 10
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 10
Molecular interaction fields in drug discovery: recent advances and future perspectives 10
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 9
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies. 9
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 9
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 8
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 8
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 8
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells 7
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease 7
Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors 7
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 7
Simple choline esters as potential anti-Alzheimer agents 7
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 7
Rational drug design of DNA G-quadruplex binders using in silico approaches 7
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 7
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 6
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? 6
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach. 6
Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine 6
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 5
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach 5
Totale 1.916
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Categoria #
all - tutte 24.055
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.055
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020116 0 0 0 2 7 2 15 11 16 5 17 41
2020/2021153 4 4 22 13 23 17 24 4 15 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024503 85 68 48 36 42 136 16 46 6 20 0 0
Totale 2.001