IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 2.304
AS - Asia 1.304
EU - Europa 977
SA - Sud America 269
AF - Africa 34
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 4.896
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Nazione #
US - Stati Uniti d'America 2.230
SG - Singapore 555
IT - Italia 471
CN - Cina 360
BR - Brasile 209
IN - India 176
DE - Germania 131
GB - Regno Unito 116
VN - Vietnam 89
SE - Svezia 66
CA - Canada 53
FI - Finlandia 52
UA - Ucraina 48
HK - Hong Kong 31
AR - Argentina 26
JP - Giappone 22
ID - Indonesia 15
ES - Italia 14
ZA - Sudafrica 14
MX - Messico 13
EE - Estonia 12
CO - Colombia 9
NL - Olanda 9
RU - Federazione Russa 8
BD - Bangladesh 7
CZ - Repubblica Ceca 7
FR - Francia 7
IQ - Iraq 7
PL - Polonia 7
CL - Cile 5
DZ - Algeria 5
EC - Ecuador 5
IR - Iran 5
LT - Lituania 5
TN - Tunisia 5
TR - Turchia 5
EG - Egitto 4
PE - Perù 4
SA - Arabia Saudita 4
UY - Uruguay 4
UZ - Uzbekistan 4
EU - Europa 3
KR - Corea 3
MA - Marocco 3
PK - Pakistan 3
RO - Romania 3
TW - Taiwan 3
VE - Venezuela 3
AL - Albania 2
AT - Austria 2
BO - Bolivia 2
CH - Svizzera 2
DK - Danimarca 2
IE - Irlanda 2
IL - Israele 2
KG - Kirghizistan 2
MY - Malesia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
PY - Paraguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
CR - Costa Rica 1
CU - Cuba 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GP - Guadalupe 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KE - Kenya 1
KW - Kuwait 1
LC - Santa Lucia 1
LV - Lettonia 1
MD - Moldavia 1
NG - Nigeria 1
NP - Nepal 1
PH - Filippine 1
PR - Porto Rico 1
PS - Palestinian Territory 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
TT - Trinidad e Tobago 1
Totale 4.896
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Città #
Dallas 432
Chandler 295
Singapore 251
Ashburn 139
Santa Clara 137
Hefei 132
Bengaluru 131
Milan 108
Lawrence 99
Princeton 99
Munich 98
London 84
Chicago 70
Wilmington 61
Beijing 48
Catanzaro 42
Ho Chi Minh City 37
Los Angeles 37
Ottawa 35
Turku 35
Des Moines 30
Hong Kong 28
São Paulo 25
Hanoi 20
Tokyo 19
Brooklyn 18
New York 16
San Nicola Manfredi 16
Helsinki 15
Rome 15
Shanghai 15
Palermo 14
San Francisco 14
Seattle 13
Boardman 12
Washington 12
Hanover 11
Pune 11
Chennai 10
Johannesburg 9
Redmond 9
Aversa 8
Charlotte 8
Guangzhou 8
Norwalk 8
Boston 7
Curitiba 7
Denver 7
Jakarta 7
Olomouc 7
The Dalles 7
Crotone 6
Messina 6
Naples 6
San Mateo 6
Stockholm 6
Warsaw 6
Cagliari 5
Columbus 5
Council Bluffs 5
Dongyang 5
Florence 5
Lamezia Terme 5
Montreal 5
Napoli 5
Rio de Janeiro 5
San Jose 5
Shenzhen 5
Toronto 5
Weihai 5
Assago 4
Brasília 4
Casoria 4
Catania 4
Guayaquil 4
Haiphong 4
Heidesheim 4
Hải Dương 4
Mexico City 4
Montevideo 4
Phoenix 4
Porto Alegre 4
Redwood City 4
Santander 4
Siena 4
Tashkent 4
Zhengzhou 4
Alassio 3
Ballabio 3
Belo Horizonte 3
Biên Hòa 3
Bogotá 3
Cosenza 3
Dhaka 3
Fontebuona 3
Fortaleza 3
Genoa 3
Hyderabad 3
Jiaxing 3
Lahore 3
Totale 2.984
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Nome #
A Candidate multi-targeting approach to block the CD98hc oncoprotein 89
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 82
GBPM: applicazione al docking molecolare 80
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 72
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 65
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 65
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 64
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 63
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 63
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 63
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 60
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 59
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 58
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 58
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 57
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 57
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 56
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 54
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 54
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 54
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 54
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 53
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 52
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 52
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 51
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 50
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 50
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 50
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 50
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 49
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 48
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 48
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 48
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 48
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 48
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 48
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 48
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 47
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 47
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 47
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 47
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 46
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 46
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 46
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 45
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 44
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 44
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 44
Computer-based techniques for lead identification and optimization i: Basics 42
Neurodegeneration: can metabolites from Eremurus persicus help? 41
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 41
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 41
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 41
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 41
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 40
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 40
Identification of new G-quadruplex binders by combined virtual screening approaches. 40
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 39
The non-coding RNA landscape of plasma cell dyscrasias 39
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 38
Metodi computazionali e nutraceutica 38
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 38
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 37
Exploring new chemical functionalities to improve aromatase inhibition of steroids 37
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 36
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 36
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 36
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 35
An overview on olfaction in the biological, analytical, computational, and machine learning fields 35
Identification of SET/EED dual binders as innovative PRC2 inhibitors 34
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 34
Computational study on DNA G-quadruplex binding compounds 34
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? 34
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains. 34
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 33
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 33
Computational approaches for discovery and optimization of G-quadruplex binders 33
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 31
Docking comparativo nello sviluppo di ligandi per il DNA G-quadruplex 31
Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir containing regimens 31
Molecular interaction fields in drug discovery: recent advances and future perspectives 31
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 31
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 31
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 30
Computer-based techniques for lead identification and optimization I: Basics 30
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 30
Structure-based pharmacophore modeling of DNA G-Quadruplex ligand-complexes. 30
Simple choline esters as potential anti-Alzheimer agents 29
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 29
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 29
Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral treated HIV-1 infected patients, all naïve to integrase inhibitors 29
New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors 29
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 29
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 28
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity 28
Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage 28
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 28
null 28
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 27
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 27
Totale 4.377
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Categoria #
all - tutte 52.690
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.690
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021123 0 0 0 13 23 17 24 4 15 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.483 181 98 51 37 115 171 78 46 193 64 170 279
2025/20261.493 192 357 526 418 0 0 0 0 0 0 0 0
Totale 5.020