IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 1.699
EU - Europa 883
AS - Asia 741
SA - Sud America 60
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 3.404
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Nazione #
US - Stati Uniti d'America 1.650
SG - Singapore 495
IT - Italia 459
CN - Cina 154
GB - Regno Unito 105
DE - Germania 99
SE - Svezia 62
BR - Brasile 49
FI - Finlandia 46
CA - Canada 42
UA - Ucraina 41
IN - India 31
JP - Giappone 18
HK - Hong Kong 15
EE - Estonia 12
ES - Italia 10
NL - Olanda 8
CZ - Repubblica Ceca 7
FR - Francia 6
DZ - Algeria 5
IR - Iran 5
MX - Messico 5
RU - Federazione Russa 5
TR - Turchia 4
CL - Cile 3
EU - Europa 3
RO - Romania 3
SA - Arabia Saudita 3
UY - Uruguay 3
VN - Vietnam 3
ZA - Sudafrica 3
AL - Albania 2
AT - Austria 2
BD - Bangladesh 2
CH - Svizzera 2
DK - Danimarca 2
EG - Egitto 2
IE - Irlanda 2
IL - Israele 2
KR - Corea 2
LT - Lituania 2
NZ - Nuova Zelanda 2
PL - Polonia 2
PT - Portogallo 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AU - Australia 1
BO - Bolivia 1
CO - Colombia 1
EC - Ecuador 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
KE - Kenya 1
KG - Kirghizistan 1
LV - Lettonia 1
MY - Malesia 1
NG - Nigeria 1
PE - Perù 1
PH - Filippine 1
PK - Pakistan 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 3.404
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Città #
Chandler 295
Singapore 229
Santa Clara 134
Ashburn 114
Milan 108
Lawrence 99
Princeton 99
London 83
Munich 68
Chicago 66
Wilmington 61
Catanzaro 42
Ottawa 35
Turku 31
Des Moines 30
Los Angeles 24
San Nicola Manfredi 16
Shanghai 15
Tokyo 15
Palermo 14
Helsinki 13
Hong Kong 13
Rome 13
Seattle 13
Washington 12
Hanover 11
Pune 11
Redmond 9
Aversa 8
Brooklyn 8
Guangzhou 8
New York 8
Norwalk 8
Beijing 7
Charlotte 7
Olomouc 7
San Francisco 7
The Dalles 7
Boardman 6
Crotone 6
Messina 6
Naples 6
San Mateo 6
São Paulo 6
Cagliari 5
Council Bluffs 5
Denver 5
Dongyang 5
Florence 5
Lamezia Terme 5
Napoli 5
Shenzhen 5
Weihai 5
Assago 4
Boston 4
Casoria 4
Catania 4
Chennai 4
Heidesheim 4
Redwood City 4
Santander 4
Siena 4
Zhengzhou 4
Alassio 3
Ballabio 3
Cosenza 3
Fontebuona 3
Genoa 3
Hyderabad 3
Jiaxing 3
Latina 3
Mexico City 3
Montevideo 3
Pachino 3
Pavia 3
Rio de Janeiro 3
San Jose 3
Sellia Marina 3
Soverato Marina 3
Treviso 3
Vallefiorita 3
Vasto 3
Xi'an 3
Amaroni 2
Ankara 2
Atlanta 2
Bari 2
Belford Roxo 2
Bengbu 2
Buffalo 2
Caulonia 2
Cincinnati 2
Cisterna di Latina 2
Clearwater 2
Dublin 2
Essen 2
Fuzhou 2
Gallipoli 2
Grottaglie 2
Houston 2
Totale 1.963
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Nome #
GBPM: applicazione al docking molecolare 72
A Candidate multi-targeting approach to block the CD98hc oncoprotein 64
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 62
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 58
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 52
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 51
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 49
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 48
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 47
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 46
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 45
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 45
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 44
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 44
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 43
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 42
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 42
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 42
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 41
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 41
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 41
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 41
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 41
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 40
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 39
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 39
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 39
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 39
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 38
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 38
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 38
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 37
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 37
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 35
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 35
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 34
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 34
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 34
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 33
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 33
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 33
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 32
Metodi computazionali e nutraceutica 32
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 31
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 31
Computer-based techniques for lead identification and optimization i: Basics 31
Exploring new chemical functionalities to improve aromatase inhibition of steroids 30
Computational study on DNA G-quadruplex binding compounds 30
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 30
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 30
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 29
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 29
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 29
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 29
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 29
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 29
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 28
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 28
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 28
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 28
null 28
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 27
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 27
Identification of new G-quadruplex binders by combined virtual screening approaches. 27
Computational approaches for discovery and optimization of G-quadruplex binders 27
The non-coding RNA landscape of plasma cell dyscrasias 27
Identification of SET/EED dual binders as innovative PRC2 inhibitors 26
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 26
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 25
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 25
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 24
New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation. 22
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 22
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 22
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 22
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 22
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 22
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 21
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 21
Molecular interaction fields in drug discovery: recent advances and future perspectives 21
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 20
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 20
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 20
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 19
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 19
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids 18
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 18
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease 18
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity 18
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 18
Rational drug design of DNA G-quadruplex binders using in silico approaches 18
Docking comparativo per lo sviluppo di ligandi per il DNA G-Quadruplex 18
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 18
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies. 18
An overview on olfaction in the biological, analytical, computational, and machine learning fields 18
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 17
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 17
Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors 16
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 16
Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine 16
Totale 3.163
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Categoria #
all - tutte 46.585
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.585
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021153 4 4 22 13 23 17 24 4 15 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.483 181 98 51 37 115 171 78 46 193 64 170 279
Totale 3.527