IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 3.179
AS - Asia 1.933
EU - Europa 1.058
SA - Sud America 335
AF - Africa 43
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
Totale 6.557
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Nazione #
US - Stati Uniti d'America 3.085
SG - Singapore 893
IT - Italia 508
CN - Cina 470
BR - Brasile 246
IN - India 187
VN - Vietnam 185
DE - Germania 137
GB - Regno Unito 124
SE - Svezia 66
CA - Canada 58
FI - Finlandia 54
UA - Ucraina 52
HK - Hong Kong 51
AR - Argentina 38
JP - Giappone 22
MX - Messico 21
ID - Indonesia 20
ES - Italia 18
IQ - Iraq 18
ZA - Sudafrica 17
NL - Olanda 15
BD - Bangladesh 14
FR - Francia 14
CO - Colombia 12
EE - Estonia 12
RU - Federazione Russa 10
CL - Cile 8
CZ - Repubblica Ceca 7
EC - Ecuador 7
PL - Polonia 7
TR - Turchia 7
UZ - Uzbekistan 7
DZ - Algeria 6
KR - Corea 6
PK - Pakistan 6
UY - Uruguay 6
IR - Iran 5
LT - Lituania 5
PY - Paraguay 5
TN - Tunisia 5
VE - Venezuela 5
BO - Bolivia 4
EG - Egitto 4
JO - Giordania 4
KE - Kenya 4
KZ - Kazakistan 4
MA - Marocco 4
PE - Perù 4
RO - Romania 4
SA - Arabia Saudita 4
TW - Taiwan 4
AT - Austria 3
DO - Repubblica Dominicana 3
EU - Europa 3
IE - Irlanda 3
IL - Israele 3
MY - Malesia 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
CH - Svizzera 2
CW - ???statistics.table.value.countryCode.CW??? 2
DK - Danimarca 2
HN - Honduras 2
HR - Croazia 2
KG - Kirghizistan 2
MD - Moldavia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BY - Bielorussia 1
CR - Costa Rica 1
CU - Cuba 1
CY - Cipro 1
GE - Georgia 1
GP - Guadalupe 1
GR - Grecia 1
GT - Guatemala 1
HU - Ungheria 1
KH - Cambogia 1
KW - Kuwait 1
LC - Santa Lucia 1
LV - Lettonia 1
NP - Nepal 1
PA - Panama 1
PH - Filippine 1
QA - Qatar 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 6.555
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Città #
San Jose 550
Dallas 433
Ashburn 350
Chandler 295
Singapore 281
Santa Clara 146
Hefei 131
Bengaluru 130
Milan 111
Lawrence 99
Princeton 99
Munich 98
London 86
Beijing 76
Ho Chi Minh City 74
Chicago 73
Wilmington 61
Hong Kong 48
Los Angeles 43
Catanzaro 42
Hanoi 39
Ottawa 35
Turku 35
Des Moines 30
São Paulo 29
New York 21
Rome 21
Tokyo 19
Brooklyn 18
Helsinki 17
San Nicola Manfredi 16
Shanghai 16
Palermo 14
San Francisco 14
Boardman 13
Haiphong 13
Seattle 13
Chennai 12
Washington 12
Hanover 11
Johannesburg 11
Pune 11
Guangzhou 10
Redmond 9
Aversa 8
Charlotte 8
Norwalk 8
Orem 8
Rio de Janeiro 8
Biên Hòa 7
Boston 7
Curitiba 7
Denver 7
Hải Dương 7
Jakarta 7
Olomouc 7
Tashkent 7
The Dalles 7
Toronto 7
Crotone 6
Messina 6
Montreal 6
Naples 6
San Mateo 6
Stockholm 6
Warsaw 6
Cagliari 5
Columbus 5
Council Bluffs 5
Dhaka 5
Dongyang 5
Florence 5
Guayaquil 5
Lahore 5
Lamezia Terme 5
Mexico City 5
Montevideo 5
Napoli 5
Phoenix 5
Shenzhen 5
Weihai 5
Amman 4
Amsterdam 4
Assago 4
Bari 4
Bogotá 4
Brasília 4
Buenos Aires 4
Buffalo 4
Casoria 4
Catania 4
Da Nang 4
Genoa 4
Heidesheim 4
Manchester 4
Mumbai 4
Nairobi 4
Nola 4
Porto Alegre 4
Quảng Ngãi 4
Totale 3.968
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Nome #
A Candidate multi-targeting approach to block the CD98hc oncoprotein 106
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 98
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 95
GBPM: applicazione al docking molecolare 92
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 86
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 83
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 83
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 83
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 81
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 78
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 76
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 75
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 74
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 73
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 72
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 71
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 70
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 70
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 70
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 69
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 69
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 68
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 67
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 67
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 66
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 66
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 66
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 64
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 63
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 62
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 62
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 62
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 61
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 61
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 61
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 61
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 60
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 60
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 60
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 59
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 59
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 59
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 59
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 58
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 58
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 58
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 57
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 57
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 56
Computer-based techniques for lead identification and optimization i: Basics 56
The non-coding RNA landscape of plasma cell dyscrasias 55
An overview on olfaction in the biological, analytical, computational, and machine learning fields 55
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 54
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 53
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 53
Identification of new G-quadruplex binders by combined virtual screening approaches. 53
Identification of SET/EED dual binders as innovative PRC2 inhibitors 52
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 51
Neurodegeneration: can metabolites from Eremurus persicus help? 51
Metodi computazionali e nutraceutica 51
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 51
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 50
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 50
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 49
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 49
Exploring new chemical functionalities to improve aromatase inhibition of steroids 49
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 48
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 48
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 46
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 46
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 46
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 45
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains. 44
Computer-based techniques for lead identification and optimization I: Basics 43
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity 43
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? 43
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids 42
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 42
Computational study on DNA G-quadruplex binding compounds 42
Docking comparativo nello sviluppo di ligandi per il DNA G-quadruplex 42
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 42
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease 41
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 41
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 41
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 40
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 40
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 40
Computational approaches for discovery and optimization of G-quadruplex binders 40
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers 40
Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir containing regimens 39
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 38
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 38
Molecular interaction fields in drug discovery: recent advances and future perspectives 38
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 38
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 38
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 37
Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage 37
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 37
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 37
Simple choline esters as potential anti-Alzheimer agents 36
Totale 5.671
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Categoria #
all - tutte 57.457
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.457
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202127 0 0 0 0 0 0 0 0 0 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.473 181 98 51 37 115 171 77 46 190 64 168 275
2025/20263.177 191 354 524 440 311 166 395 235 399 162 0 0
Totale 6.694