IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 1.551
EU - Europa 758
AS - Asia 622
SA - Sud America 11
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 2.956
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Nazione #
US - Stati Uniti d'America 1.510
IT - Italia 446
SG - Singapore 403
CN - Cina 154
GB - Regno Unito 93
SE - Svezia 60
DE - Germania 41
UA - Ucraina 41
CA - Canada 39
IN - India 24
FI - Finlandia 15
HK - Hong Kong 15
JP - Giappone 13
EE - Estonia 12
ES - Italia 8
NL - Olanda 8
CZ - Repubblica Ceca 7
BR - Brasile 5
IR - Iran 5
RU - Federazione Russa 5
CL - Cile 3
DZ - Algeria 3
EU - Europa 3
FR - Francia 3
RO - Romania 3
CH - Svizzera 2
DK - Danimarca 2
IE - Irlanda 2
KR - Corea 2
LT - Lituania 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
UY - Uruguay 2
ZA - Sudafrica 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AU - Australia 1
CO - Colombia 1
EG - Egitto 1
GR - Grecia 1
HR - Croazia 1
IL - Israele 1
LV - Lettonia 1
MX - Messico 1
MY - Malesia 1
NG - Nigeria 1
PH - Filippine 1
PL - Polonia 1
PR - Porto Rico 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
TW - Taiwan 1
Totale 2.956
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Città #
Chandler 295
Singapore 140
Santa Clara 129
Milan 108
Ashburn 105
Lawrence 99
Princeton 99
London 77
Chicago 66
Wilmington 61
Catanzaro 42
Ottawa 35
Des Moines 30
Los Angeles 21
San Nicola Manfredi 16
Shanghai 15
Palermo 14
Helsinki 13
Hong Kong 13
Rome 12
Washington 12
Hanover 11
Pune 11
Munich 10
Seattle 10
Tokyo 10
Redmond 9
Aversa 8
Guangzhou 8
Norwalk 8
Beijing 7
Olomouc 7
Boardman 6
Crotone 6
Messina 6
San Mateo 6
Cagliari 5
Council Bluffs 5
Dongyang 5
Florence 5
Lamezia Terme 5
Napoli 5
Shenzhen 5
Weihai 5
Assago 4
Casoria 4
Catania 4
Heidesheim 4
Redwood City 4
Santander 4
Siena 4
Zhengzhou 4
Alassio 3
Ballabio 3
Cosenza 3
Fontebuona 3
Genoa 3
Hyderabad 3
Jiaxing 3
Latina 3
Pachino 3
Pavia 3
San Jose 3
Soverato Marina 3
Treviso 3
Vallefiorita 3
Vasto 3
Xi'an 3
Amaroni 2
Bengbu 2
Caulonia 2
Cisterna di Latina 2
Clearwater 2
Dublin 2
Essen 2
Fuzhou 2
Gallipoli 2
Grottaglie 2
Jinan 2
Klaipėda 2
Labico 2
Leeds 2
Montevideo 2
Mountain View 2
Nicotera 2
Padova 2
Patna 2
Pizzo 2
Porto 2
Ragusa 2
Reggio Calabria 2
Romainville 2
Rozzano 2
Rui'an 2
San Cristóbal de La Laguna 2
Serra San Bruno 2
Sorrento 2
Taranto 2
Toronto 2
Vigliano Biellese 2
Totale 1.709
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Nome #
GBPM: applicazione al docking molecolare 69
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 58
A Candidate multi-targeting approach to block the CD98hc oncoprotein 58
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 53
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 49
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 46
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 43
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 42
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 41
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 40
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 40
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 40
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 39
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 39
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 38
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 38
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 37
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 37
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 37
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 36
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 36
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 36
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 36
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 36
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 35
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 34
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 34
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 34
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 33
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 33
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 33
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 33
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 33
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 32
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 32
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 31
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 30
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 30
Metodi computazionali e nutraceutica 30
Computational study on DNA G-quadruplex binding compounds 29
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 29
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 28
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 28
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 28
null 28
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 27
Exploring new chemical functionalities to improve aromatase inhibition of steroids 27
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 27
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 27
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 27
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 27
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 27
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 26
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 26
Computational approaches for discovery and optimization of G-quadruplex binders 26
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 26
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 25
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 24
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 24
Identification of new G-quadruplex binders by combined virtual screening approaches. 24
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 24
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 24
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 24
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 24
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 23
Identification of SET/EED dual binders as innovative PRC2 inhibitors 23
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 23
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 22
The non-coding RNA landscape of plasma cell dyscrasias 22
New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation. 21
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 21
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 21
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase 20
Computer-based techniques for lead identification and optimization i: Basics 20
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 19
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 19
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 18
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 18
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 18
Molecular interaction fields in drug discovery: recent advances and future perspectives 18
Molecular docking, synthesis and biological evaluation of indomethacin analogs as novel cyclooxygenase inhibitors. 18
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 17
Rational drug design of DNA G-quadruplex binders using in silico approaches 17
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 17
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 16
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 16
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 16
Docking comparativo per lo sviluppo di ligandi per il DNA G-Quadruplex 16
Structural analysis against HCV polymerase in presence of natural resistance-associated substitutions in HCV isolates from DAA-naïve patients 16
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies. 16
Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors 15
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 15
Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine 15
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids 14
SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021 14
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data 14
An overview on olfaction in the biological, analytical, computational, and machine learning fields 14
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 13
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 13
Docking comparativo nello sviluppo di ligandi per il DNA G-quadruplex 13
Totale 2.798
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Categoria #
all - tutte 40.693
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.693
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202058 0 0 0 0 0 0 0 0 0 0 17 41
2020/2021153 4 4 22 13 23 17 24 4 15 13 9 5
2021/2022294 2 2 7 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.033 181 98 51 37 115 169 78 46 191 64 3 0
Totale 3.077