IRIS
COSTA, GIOSUE'
 Distribuzione geografica
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Continente #
NA - Nord America 3.961
AS - Asia 2.002
EU - Europa 1.118
SA - Sud America 338
Continente sconosciuto - Info sul continente non disponibili 144
AF - Africa 47
OC - Oceania 4
Totale 7.614
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Nazione #
US - Stati Uniti d'America 3.837
SG - Singapore 915
IT - Italia 557
CN - Cina 495
BR - Brasile 249
IN - India 187
VN - Vietnam 185
DE - Germania 139
GB - Regno Unito 125
CA - Canada 76
SE - Svezia 66
HK - Hong Kong 59
FI - Finlandia 54
UA - Ucraina 52
AR - Argentina 38
JP - Giappone 25
BD - Bangladesh 23
MX - Messico 22
ID - Indonesia 20
NL - Olanda 19
ZA - Sudafrica 19
ES - Italia 18
IQ - Iraq 18
FR - Francia 14
CO - Colombia 12
EE - Estonia 12
RU - Federazione Russa 10
CL - Cile 8
PK - Pakistan 8
PL - Polonia 8
CZ - Repubblica Ceca 7
EC - Ecuador 7
TR - Turchia 7
UZ - Uzbekistan 7
DZ - Algeria 6
KR - Corea 6
UY - Uruguay 6
EG - Egitto 5
IR - Iran 5
LT - Lituania 5
PY - Paraguay 5
TN - Tunisia 5
VE - Venezuela 5
BO - Bolivia 4
IE - Irlanda 4
JO - Giordania 4
KE - Kenya 4
KZ - Kazakistan 4
MA - Marocco 4
PE - Perù 4
RO - Romania 4
SA - Arabia Saudita 4
TW - Taiwan 4
AL - Albania 3
AT - Austria 3
CR - Costa Rica 3
CW - ???statistics.table.value.countryCode.CW??? 3
DO - Repubblica Dominicana 3
EU - Europa 3
GT - Guatemala 3
IL - Israele 3
MY - Malesia 3
PR - Porto Rico 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
CH - Svizzera 2
DK - Danimarca 2
HN - Honduras 2
HR - Croazia 2
JM - Giamaica 2
KG - Kirghizistan 2
MD - Moldavia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
PT - Portogallo 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BH - Bahrain 1
BY - Bielorussia 1
CU - Cuba 1
CY - Cipro 1
GE - Georgia 1
GP - Guadalupe 1
GR - Grecia 1
HU - Ungheria 1
KH - Cambogia 1
KW - Kuwait 1
LC - Santa Lucia 1
LU - Lussemburgo 1
LV - Lettonia 1
NI - Nicaragua 1
NP - Nepal 1
Totale 7.469
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Città #
San Jose 781
Dallas 438
Ashburn 422
Chandler 295
Singapore 292
Santa Clara 168
Council Bluffs 139
Hefei 131
Bengaluru 130
Milan 114
Princeton 103
Lawrence 99
Munich 98
Beijing 90
London 88
Chicago 82
Ho Chi Minh City 74
Wilmington 61
Los Angeles 60
Hong Kong 56
Catanzaro 42
Hanoi 39
Phoenix 39
Ottawa 35
Turku 35
Des Moines 30
São Paulo 29
New York 28
Rome 23
Tokyo 22
Brooklyn 20
Shanghai 18
Helsinki 17
San Nicola Manfredi 16
San Francisco 15
Boardman 14
Palermo 14
Seattle 14
Haiphong 13
Chennai 12
Washington 12
Hanover 11
Johannesburg 11
Pune 11
Guangzhou 10
Boston 9
Redmond 9
Toronto 9
Aversa 8
Charlotte 8
Denver 8
Florence 8
Norwalk 8
Orem 8
Rio de Janeiro 8
The Dalles 8
Bari 7
Biên Hòa 7
Curitiba 7
Hải Dương 7
Jakarta 7
Montreal 7
Naples 7
Olomouc 7
Tashkent 7
Warsaw 7
Amsterdam 6
Atlanta 6
Crotone 6
Lahore 6
Messina 6
Mexico City 6
San Mateo 6
Stockholm 6
Brasília 5
Cagliari 5
Columbus 5
Dhaka 5
Dongyang 5
Frankfurt am Main 5
Guayaquil 5
Lamezia Terme 5
Las Vegas 5
Montevideo 5
Napoli 5
Pretoria 5
Shenzhen 5
Weihai 5
Amman 4
Assago 4
Bogotá 4
Buenos Aires 4
Buffalo 4
Casoria 4
Catania 4
Da Nang 4
Genoa 4
Heidesheim 4
Manchester 4
Mumbai 4
Totale 4.578
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Nome #
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 119
A Candidate multi-targeting approach to block the CD98hc oncoprotein 118
A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine. 106
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 104
Application of standard and enhanced sampling approaches on non-canonical structures of DNA and RNA 100
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy 96
GBPM: applicazione al docking molecolare 94
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 91
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 88
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity 83
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin 82
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 82
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses 82
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation 81
In Silico and In Vitro Study of Antioxidant Potential of Urolithins 80
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures 80
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 80
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 79
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 79
(Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies. 76
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 76
3-Acetyl-25-diaryl-23-dihydro-134-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B 74
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships. 74
Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach 74
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 74
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 73
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques 73
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 70
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 70
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 69
Molecular recognition studies of dasabuvir, tegobuvir, and setrobuvir against natural Hepatitis C Virus NS5B polymerase variants. 69
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands 68
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 67
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 67
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 67
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds 66
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 66
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 66
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment 66
An overview on olfaction in the biological, analytical, computational, and machine learning fields 66
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas 65
In silico identification and biological evaluation of antioxidant food components endowed with IX and XII hCA inhibition 65
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 64
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 63
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 63
The non-coding RNA landscape of plasma cell dyscrasias 62
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 62
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 61
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 61
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 61
Computer-based techniques for lead identification and optimization i: Basics 61
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 61
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line. 60
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity 59
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids. 59
Identification and Structural Characterization of Novel Genetic Elements in HIV-1 - V3 Loop Regulating Co-Receptor Usage 59
Identification of SET/EED dual binders as innovative PRC2 inhibitors 58
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 58
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 58
Kaempferol as Selective Human MAO-A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies 58
Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids 58
Identification of new G-quadruplex binders by combined virtual screening approaches. 57
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach 56
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients 56
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors 56
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 56
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma 55
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 55
Neurodegeneration: can metabolites from Eremurus persicus help? 55
Metodi computazionali e nutraceutica 55
Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease 53
Computer-based techniques for lead identification and optimization I: Basics 53
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 52
Exploring new chemical functionalities to improve aromatase inhibition of steroids 52
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers 50
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage 48
Conformation and stability of intramolecular telomeric g-quadruplexes: sequence effects in the loops 48
Structural Modeling of New Polymorphism Clusters of HCV Polymerase Isolated from Direct-Acting Antiviral Naïve Patients: Focus on Dasabuvir and Setrobuvir Binding Affinity 48
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 48
Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? 47
Molecular interaction fields in drug discovery: recent advances and future perspectives 47
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains. 47
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 46
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products 46
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 46
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids 45
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 45
Computational study on DNA G-quadruplex binding compounds 45
Docking comparativo nello sviluppo di ligandi per il DNA G-quadruplex 45
Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies 45
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2 44
Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir containing regimens 44
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance 44
Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations 43
Docking comparativo per lo sviluppo di ligandi per il DNA G-Quadruplex 43
The polymorphisms of DNA g-quadruplex investigated by docking experiments with telomestatin enantiomers 43
Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity 43
Molecular Recognition Of Dna G-Quadruplex Ligands By Different Docking Methods 42
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029 42
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors 42
Totale 6.358
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Categoria #
all - tutte 67.099
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.099
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022283 0 0 0 59 13 4 18 68 22 37 58 4
2022/2023935 210 42 47 57 93 77 11 67 154 58 95 24
2023/2024546 85 68 48 36 42 136 16 46 6 20 26 17
2024/20251.473 181 98 51 37 115 171 77 46 190 64 168 275
2025/20263.396 191 354 524 440 311 166 395 235 399 228 112 41
2026/2027701 45 135 356 165 0 0 0 0 0 0 0 0
Totale 7.614