IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 7.656
AS - Asia 4.027
EU - Europa 1.627
SA - Sud America 1.001
Continente sconosciuto - Info sul continente non disponibili 147
AF - Africa 78
OC - Oceania 4
Totale 14.540
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Nazione #
US - Stati Uniti d'America 7.449
SG - Singapore 1.778
CN - Cina 1.012
BR - Brasile 783
IT - Italia 727
VN - Vietnam 477
IN - India 355
DE - Germania 209
GB - Regno Unito 180
SE - Svezia 175
CA - Canada 132
HK - Hong Kong 116
AR - Argentina 93
FI - Finlandia 78
UA - Ucraina 63
BD - Bangladesh 53
MX - Messico 41
ID - Indonesia 40
EC - Ecuador 36
IQ - Iraq 31
ES - Italia 30
NL - Olanda 29
ZA - Sudafrica 29
TR - Turchia 25
CO - Colombia 22
EE - Estonia 22
JP - Giappone 22
FR - Francia 20
PY - Paraguay 19
RU - Federazione Russa 17
VE - Venezuela 17
MA - Marocco 15
PK - Pakistan 13
UY - Uruguay 12
CL - Cile 11
CZ - Repubblica Ceca 11
TN - Tunisia 10
PL - Polonia 9
SA - Arabia Saudita 9
AT - Austria 8
DO - Repubblica Dominicana 8
IL - Israele 8
JO - Giordania 8
NP - Nepal 8
RO - Romania 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
TW - Taiwan 7
CR - Costa Rica 6
EU - Europa 6
KR - Corea 6
LT - Lituania 6
PE - Perù 6
AL - Albania 5
AZ - Azerbaigian 5
DZ - Algeria 5
EG - Egitto 5
GT - Guatemala 5
IE - Irlanda 5
KE - Kenya 5
MY - Malesia 5
GR - Grecia 4
IR - Iran 4
KZ - Kazakistan 4
SY - Repubblica araba siriana 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BG - Bulgaria 3
CY - Cipro 3
DK - Danimarca 3
MD - Moldavia 3
PA - Panama 3
PH - Filippine 3
PR - Porto Rico 3
AU - Australia 2
BH - Bahrain 2
BY - Bielorussia 2
GA - Gabon 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
MN - Mongolia 2
NG - Nigeria 2
PS - Palestinian Territory 2
PT - Portogallo 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
AO - Angola 1
BO - Bolivia 1
BZ - Belize 1
CI - Costa d'Avorio 1
GE - Georgia 1
GH - Ghana 1
GY - Guiana 1
HN - Honduras 1
KH - Cambogia 1
KW - Kuwait 1
LB - Libano 1
MC - Monaco 1
MK - Macedonia 1
Totale 14.389
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Città #
Dallas 1.787
San Jose 1.147
Chandler 571
Ashburn 550
Singapore 450
Santa Clara 341
Council Bluffs 278
Milan 271
Hefei 265
Bengaluru 263
Princeton 256
Lawrence 251
Beijing 180
Ho Chi Minh City 171
Munich 153
Wilmington 134
London 114
Chicago 108
Hong Kong 107
Ottawa 89
Des Moines 86
Hanoi 83
Los Angeles 81
São Paulo 78
Helsinki 52
Shanghai 48
Catanzaro 43
New York 42
Phoenix 34
Boardman 33
The Dalles 31
Rome 28
Haiphong 26
Norwalk 24
Rio de Janeiro 24
Da Nang 23
Shenzhen 23
Guangzhou 22
Brooklyn 20
Pune 19
Tokyo 19
Curitiba 18
Johannesburg 18
San Francisco 18
Turku 18
Washington 18
Amsterdam 16
Atlanta 16
Biên Hòa 16
West Jordan 16
Guayaquil 15
Bonn 14
Buffalo 14
Redwood City 14
Thái Bình 14
Columbus 13
Jiaxing 13
Mexico City 13
Napoli 13
Porto Alegre 13
Redmond 13
Palermo 12
Ribeirão Preto 12
Bari 11
Brasília 11
Chennai 11
Denver 11
Jakarta 11
Montevideo 11
Naples 11
Seattle 11
Boston 10
Campinas 10
Guarulhos 10
Olomouc 10
Orem 10
Stockholm 10
Ankara 9
Belo Horizonte 9
Montreal 9
Quito 9
Santo André 9
Toronto 9
Hanover 8
Lấp Vò 8
Manaus 8
Manchester 8
Wuhan 8
Amman 7
Augusta 7
Baghdad 7
Buenos Aires 7
Cagliari 7
Can Tho 7
Caracas 7
Florence 7
Huế 7
Hải Dương 7
Istanbul 7
Latina 7
Totale 8.978
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 650
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 536
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 506
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 119
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 103
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 98
GBPM: applicazione al docking molecolare 94
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 93
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 90
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 88
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 88
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 84
A Computational pathway toward the rational design of azinomycin analogues 84
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 84
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 83
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 82
Chemioterapici antifungini 80
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 80
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 80
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 80
Computer-based techniques for lead identification and optimization II: Advanced search methods 80
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 79
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 79
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 78
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 78
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 76
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 76
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 74
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 74
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 73
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 72
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 72
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 71
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 71
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 70
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 69
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 69
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 67
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 67
CoMFA studies of non covalent monoamine oxidase inhibitors 67
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 67
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 67
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 67
MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers 67
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 66
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 66
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 66
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 64
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 64
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 64
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 63
GRID-based Pharmacophore Models:Concept and Application Examples 63
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning 63
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 63
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 61
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 61
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 61
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 60
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 59
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 59
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 59
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 59
Identification of SET/EED dual binders as innovative PRC2 inhibitors 58
Conformational search of antisense nucleotides 58
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 58
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 58
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins 58
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 57
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 57
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 57
Identification of new G-quadruplex binders by combined virtual screening approaches. 57
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor 57
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties 55
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 55
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 55
Metodi computazionali e nutraceutica 55
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 55
Design, synthesis, and SAR analysis of novel selective sigma(1) ligands 55
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs 55
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 55
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 54
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 54
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 54
Composti per il G-quadruplex a struttura naftilimmidica 54
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 54
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 53
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 53
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells. 53
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 53
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives 53
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 52
Evaluation of COX-2 selectivity and molecular modeling of novel 3,3'-(1,2-ethanedyil)bis-[2-(methoxyphenyl)-thiazolidin-4-ones] with antiinflam-matory activity 52
8-Amide and 8-Carbamate Substitution Patterns as Modulators of 7-Hydroxy-4-Methylcoumarin{'}s Antidepressant Profile: Synthesis, MAO Inhibition, Cytotoxicity and Docking Studies 51
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 51
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 51
Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold 51
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 51
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 51
The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing 50
β-cyclodextrin interactions with three drugs used in inflammatory pathologies: an experimental and theoretical study 50
Totale 8.113
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Categoria #
all - tutte 130.966
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 130.966
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022625 0 0 0 137 43 20 22 138 72 52 126 15
2022/20231.768 516 71 47 137 202 146 14 131 281 96 101 26
2023/2024753 109 99 75 57 44 192 24 36 17 35 22 43
2024/20252.745 369 254 132 105 133 336 97 118 360 270 182 389
2025/20267.199 233 845 1.901 1.220 503 192 612 388 730 372 145 58
2026/2027983 83 274 558 68 0 0 0 0 0 0 0 0
Totale 14.540