IRIS
ORTUSO, Francesco
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 3.018
AS - Asia 1.374
EU - Europa 1.261
SA - Sud America 21
Continente sconosciuto - Info sul continente non disponibili 9
AF - Africa 4
OC - Oceania 1
Totale 5.688
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.916
SG - Singapore 894
IT - Italia 622
CN - Cina 365
SE - Svezia 164
DE - Germania 138
GB - Regno Unito 131
CA - Canada 94
FI - Finlandia 58
IN - India 56
UA - Ucraina 47
HK - Hong Kong 27
EE - Estonia 22
NL - Olanda 18
BR - Brasile 12
ES - Italia 10
CZ - Repubblica Ceca 9
RO - Romania 8
FR - Francia 7
EU - Europa 6
IL - Israele 6
MX - Messico 6
TR - Turchia 6
AT - Austria 4
CL - Cile 4
GR - Grecia 4
IR - Iran 4
RU - Federazione Russa 4
TW - Taiwan 4
A2 - ???statistics.table.value.countryCode.A2??? 3
DK - Danimarca 3
JP - Giappone 3
VN - Vietnam 3
CO - Colombia 2
IE - Irlanda 2
LT - Lituania 2
MY - Malesia 2
PH - Filippine 2
PT - Portogallo 2
UY - Uruguay 2
AL - Albania 1
AU - Australia 1
BG - Bulgaria 1
DO - Repubblica Dominicana 1
EG - Egitto 1
MC - Monaco 1
MD - Moldavia 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
NP - Nepal 1
PE - Perù 1
PL - Polonia 1
PR - Porto Rico 1
RE - Reunion 1
Totale 5.688
Salva come PNG Salva come JPEG
Città #
Chandler 571
Santa Clara 271
Milan 257
Princeton 252
Lawrence 251
Singapore 228
Ashburn 140
Wilmington 134
London 109
Chicago 95
Munich 95
Ottawa 88
Des Moines 86
Helsinki 50
Shanghai 45
Catanzaro 42
Norwalk 24
Guangzhou 21
Shenzhen 21
Beijing 20
Hong Kong 20
Pune 19
Los Angeles 18
Washington 17
Boardman 16
West Jordan 16
Bonn 14
Redwood City 14
Council Bluffs 13
Jiaxing 13
Napoli 13
Redmond 13
Rome 13
Palermo 12
Amsterdam 11
Olomouc 9
The Dalles 9
Buffalo 8
Hanover 8
Latina 7
San Nicola Manfredi 7
Wuhan 7
Cagliari 6
Naples 6
Reggio Calabria 6
Seattle 6
Secaucus 6
São Paulo 6
Augusta 5
Avola 5
Jyväskylä 5
Luni 5
Messina 5
Mountain View 5
Rui'an 5
Shaoxing 5
Siena 5
Taranto 5
Teramo 5
Vasto 5
Weihai 5
Xi'an 5
Ann Arbor 4
Aversa 4
Bologna 4
Castrovillari 4
Clearwater 4
Cosenza 4
Florence 4
Fuzhou 4
Horia 4
Santander 4
Taizhou 4
Wuxi 4
Afragola 3
Bari 3
Catania 3
Como 3
Dongyang 3
Ferrara 3
Giulianova 3
Gopalganj 3
Jinan 3
Lamezia Terme 3
Padova 3
Pavia 3
Phoenix 3
Rende 3
Salsomaggiore 3
San Cristóbal de La Laguna 3
Amaroni 2
Andover 2
Bagnoli di Sopra 2
Bathinda 2
Bogotá 2
Brindisi 2
Ca Mau 2
Caulonia 2
Chandigarh 2
Cicciano 2
Totale 3.299
Salva come PNG Salva come JPEG
Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 199
GBPM: applicazione al docking molecolare 69
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 69
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 66
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 62
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 53
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 53
Chemioterapici antifungini 46
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 46
A Computational pathway toward the rational design of azinomycin analogues 44
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 44
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 43
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 43
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 43
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 42
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 40
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 40
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 40
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 39
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 39
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 38
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 38
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 38
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 37
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 37
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 37
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 37
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 36
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 36
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 36
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 35
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 35
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 35
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 34
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 34
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 34
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 34
Conformational search of antisense nucleotides 33
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 33
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 33
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 32
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 32
CoMFA studies of non covalent monoamine oxidase inhibitors 32
Computer-based techniques for lead identification and optimization II: Advanced search methods 32
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 32
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 31
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 31
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 31
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 31
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 31
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 31
Metodi computazionali e nutraceutica 30
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 30
Computational methods applied to the discovery of stem cell factor ligands 29
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 29
Computational study on DNA G-quadruplex binding compounds 29
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 29
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 29
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 28
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 28
Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds 28
Sintesi di cicloalchilidenidrazo-4-ariltiazoli ad elevata attività inibitrice selettiva sulla isoforma B delle monoamminossidasi 28
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 28
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 28
The active site of acetylcholinesterase: validation of a new computational model 28
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 28
null 28
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 27
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 27
Donepezil analogs as acetylcholinesterase inhibitors 27
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 27
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 27
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study 27
MOLINE docking experiments of enzyme-ligand complexes 26
Chromatographic studies of chiral discrimination by cellulose tris(4-methylbenzoate) 26
Enzymatic and molecular modeling studies of 5-HT3 receptor ligands based on pyrroloquinoline structure and provided with acetylcholinesterase inhibitory activity 26
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 26
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents 26
Analisi “GRID di antitumorali di derivazione naturale 26
Computational approaches for discovery and optimization of G-quadruplex binders 26
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 26
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 25
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 25
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 24
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 24
GRID-based Pharmacophore Models:Concept and Application Examples 24
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 24
Development of Selenium based molecular mechanics parameters: an application to antisense nucleotides 24
Molecular modeling and enzymatic studies of the interaction of a choline analogue and acetylcholinesterase 24
Identification of new G-quadruplex binders by combined virtual screening approaches. 24
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 24
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 24
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 24
Identification of SET/EED dual binders as innovative PRC2 inhibitors 23
Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5 diaryl pyrazole inhibitors 23
Studies of substituted thiazolylhydrazones as a new scaffold for mao-inhibitory activity 23
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 23
Screening virtuale di inibitori selettivi dell’SCF 23
Progettazione razionale e sintesi di potenziali inibitori della glutatione S transferasi (GST) 23
Docking e virtual screening su composti naturali: esempi su quercitina e cucurbitacina 23
Totale 3.454
Salva come PNG Salva come JPEG
Categoria #
all - tutte 84.445
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.445
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020135 0 0 0 0 0 0 0 0 0 0 42 93
2020/2021219 11 7 9 27 26 22 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.774 516 71 47 138 202 146 14 131 283 97 103 26
2023/2024761 111 102 75 58 44 193 24 36 17 35 22 44
2024/20252.188 371 254 133 107 135 337 98 118 363 270 2 0
Totale 5.815