IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 5.639
AS - Asia 3.242
EU - Europa 1.491
SA - Sud America 956
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 4
Totale 11.403
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Nazione #
US - Stati Uniti d'America 5.474
SG - Singapore 1.382
CN - Cina 789
BR - Brasile 759
IT - Italia 661
VN - Vietnam 462
IN - India 349
DE - Germania 199
SE - Svezia 174
GB - Regno Unito 166
CA - Canada 115
AR - Argentina 85
FI - Finlandia 76
UA - Ucraina 57
HK - Hong Kong 45
ID - Indonesia 38
BD - Bangladesh 34
EC - Ecuador 34
MX - Messico 30
ZA - Sudafrica 25
NL - Olanda 23
EE - Estonia 22
ES - Italia 21
JP - Giappone 21
TR - Turchia 21
PY - Paraguay 19
CO - Colombia 18
IQ - Iraq 18
RU - Federazione Russa 16
MA - Marocco 14
VE - Venezuela 12
UY - Uruguay 11
CL - Cile 10
CZ - Repubblica Ceca 10
FR - Francia 10
PK - Pakistan 10
DO - Repubblica Dominicana 8
IL - Israele 8
PL - Polonia 8
RO - Romania 8
SA - Arabia Saudita 8
AT - Austria 6
EU - Europa 6
PE - Perù 6
UZ - Uzbekistan 6
AL - Albania 5
AZ - Azerbaigian 5
EG - Egitto 5
KE - Kenya 5
LT - Lituania 5
TN - Tunisia 5
TW - Taiwan 5
AE - Emirati Arabi Uniti 4
GR - Grecia 4
IR - Iran 4
JO - Giordania 4
MY - Malesia 4
NP - Nepal 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BG - Bulgaria 3
DK - Danimarca 3
DZ - Algeria 3
GT - Guatemala 3
IE - Irlanda 3
KR - Corea 3
AU - Australia 2
CY - Cipro 2
GA - Gabon 2
JM - Giamaica 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MD - Moldavia 2
MN - Mongolia 2
PA - Panama 2
PH - Filippine 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
SY - Repubblica araba siriana 2
AF - Afghanistan, Repubblica islamica di 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
CR - Costa Rica 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
KW - Kuwait 1
LB - Libano 1
MC - Monaco 1
MK - Macedonia 1
NG - Nigeria 1
NO - Norvegia 1
PG - Papua Nuova Guinea 1
PW - Palau 1
RE - Reunion 1
SI - Slovenia 1
SO - Somalia 1
TT - Trinidad e Tobago 1
Totale 11.403
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Città #
Dallas 1.777
Chandler 571
Singapore 357
Ashburn 336
Santa Clara 289
Hefei 266
Bengaluru 264
Milan 262
Princeton 252
Lawrence 251
San Jose 211
Ho Chi Minh City 164
Munich 153
Wilmington 134
London 112
Beijing 98
Chicago 95
Ottawa 88
Des Moines 86
Hanoi 81
São Paulo 75
Helsinki 50
Los Angeles 50
Shanghai 45
Catanzaro 42
Hong Kong 37
Boardman 31
The Dalles 30
New York 27
Haiphong 26
Norwalk 24
Da Nang 22
Rio de Janeiro 22
Guangzhou 21
Shenzhen 21
Pune 19
Curitiba 18
Tokyo 18
Turku 18
Brooklyn 17
Rome 17
Washington 17
Biên Hòa 16
Council Bluffs 16
Johannesburg 16
San Francisco 16
West Jordan 16
Guayaquil 15
Bonn 14
Redwood City 14
Thái Bình 14
Amsterdam 13
Columbus 13
Jiaxing 13
Napoli 13
Porto Alegre 13
Redmond 13
Palermo 12
Ribeirão Preto 12
Brasília 11
Buffalo 11
Jakarta 11
Campinas 10
Guarulhos 10
Montevideo 10
Olomouc 10
Stockholm 10
Belo Horizonte 9
Boston 9
Quito 9
Ankara 8
Atlanta 8
Chennai 8
Hanover 8
Lấp Vò 8
Ninh Bình 8
Seattle 8
Augusta 7
Cagliari 7
Denver 7
Huế 7
Hải Dương 7
Latina 7
Manaus 7
Naples 7
Phoenix 7
Salvador 7
San Nicola Manfredi 7
Santo André 7
Secaucus 7
Thái Nguyên 7
Wuhan 7
Bari 6
Buenos Aires 6
Caracas 6
Medellín 6
Mexico City 6
Montreal 6
Mumbai 6
Reggio Calabria 6
Totale 7.052
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 626
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 513
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 486
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 88
GBPM: applicazione al docking molecolare 84
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 82
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 77
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 73
A Computational pathway toward the rational design of azinomycin analogues 73
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 71
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 71
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 71
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 69
Chemioterapici antifungini 69
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 69
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 68
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 68
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 68
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 67
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 67
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 66
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 66
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 65
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 64
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 64
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 63
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 63
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 62
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 62
Computer-based techniques for lead identification and optimization II: Advanced search methods 61
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 61
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 57
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 57
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 57
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 57
CoMFA studies of non covalent monoamine oxidase inhibitors 57
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 56
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 55
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 55
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 54
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 54
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 54
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 54
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 54
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 54
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 53
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 53
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 52
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 52
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 51
GRID-based Pharmacophore Models:Concept and Application Examples 51
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 51
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 51
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 50
MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers 50
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 49
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 48
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 48
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning 48
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 48
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 47
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 47
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 47
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 46
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 46
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 46
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 45
Conformational search of antisense nucleotides 45
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 44
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 44
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 44
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 44
Identification of new G-quadruplex binders by combined virtual screening approaches. 44
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 44
Composti per il G-quadruplex a struttura naftilimmidica 44
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 43
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 43
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 43
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 43
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 43
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs 43
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 43
Identification of SET/EED dual binders as innovative PRC2 inhibitors 42
Conformational behavior of antineoplastic peptides dolastatin 10 and dolastatin 15 from Monte Carlo and molecular dynamics simulations molecular dynamics simulations 42
Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold 41
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 41
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives 41
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 41
Rational Identification of Ritonavir as IL-20 Receptor A Ligand Endowed with Antiproliferative Properties in Breast Cancer Cells 40
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 40
Metodi computazionali e nutraceutica 40
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 40
Coumarin versus chromone monoamine oxidase B inhibitors: Quo vadis? 40
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study 40
8-Amide and 8-Carbamate Substitution Patterns as Modulators of 7-Hydroxy-4-Methylcoumarin{'}s Antidepressant Profile: Synthesis, MAO Inhibition, Cytotoxicity and Docking Studies 39
Rational drug design of Azinomycin analogs 39
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor 39
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties 38
Conformational search of antisense nucleotides. Part 2 38
PTPRJ ligands identification and characterization 38
Totale 6.784
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Categoria #
all - tutte 112.231
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 112.231
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021117 0 0 0 0 0 0 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.768 516 71 47 137 202 146 14 131 281 96 101 26
2023/2024753 109 99 75 57 44 192 24 36 17 35 22 43
2024/20252.755 369 254 132 105 133 336 98 118 363 270 184 393
2025/20265.166 234 848 1.903 1.223 506 195 257 0 0 0 0 0
Totale 11.534