IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 5.278
AS - Asia 3.057
EU - Europa 1.478
SA - Sud America 933
AF - Africa 61
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 4
Totale 10.820
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Nazione #
US - Stati Uniti d'America 5.120
SG - Singapore 1.319
CN - Cina 781
BR - Brasile 748
IT - Italia 652
VN - Vietnam 376
IN - India 350
DE - Germania 198
SE - Svezia 174
GB - Regno Unito 168
CA - Canada 115
AR - Argentina 79
FI - Finlandia 76
UA - Ucraina 56
HK - Hong Kong 37
ID - Indonesia 36
EC - Ecuador 32
BD - Bangladesh 29
MX - Messico 24
ZA - Sudafrica 24
EE - Estonia 22
ES - Italia 21
TR - Turchia 21
JP - Giappone 20
NL - Olanda 20
CO - Colombia 18
PY - Paraguay 18
RU - Federazione Russa 14
IQ - Iraq 13
MA - Marocco 13
CZ - Repubblica Ceca 11
FR - Francia 11
UY - Uruguay 11
VE - Venezuela 10
CL - Cile 9
DO - Repubblica Dominicana 8
IL - Israele 8
PL - Polonia 8
RO - Romania 8
SA - Arabia Saudita 8
PK - Pakistan 7
AT - Austria 6
EU - Europa 6
PE - Perù 6
UZ - Uzbekistan 6
AL - Albania 5
EG - Egitto 5
KE - Kenya 5
LT - Lituania 5
TN - Tunisia 5
TW - Taiwan 5
AE - Emirati Arabi Uniti 4
AZ - Azerbaigian 4
GR - Grecia 4
IR - Iran 4
JO - Giordania 4
NP - Nepal 4
A2 - ???statistics.table.value.countryCode.A2??? 3
DK - Danimarca 3
DZ - Algeria 3
IE - Irlanda 3
KR - Corea 3
MY - Malesia 3
AU - Australia 2
BG - Bulgaria 2
GA - Gabon 2
GT - Guatemala 2
JM - Giamaica 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MD - Moldavia 2
MN - Mongolia 2
PA - Panama 2
PH - Filippine 2
PR - Porto Rico 2
PT - Portogallo 2
AF - Afghanistan, Repubblica islamica di 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
CR - Costa Rica 1
CY - Cipro 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
KW - Kuwait 1
LB - Libano 1
MC - Monaco 1
MK - Macedonia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
PG - Papua Nuova Guinea 1
PS - Palestinian Territory 1
PW - Palau 1
RE - Reunion 1
SI - Slovenia 1
SO - Somalia 1
SY - Repubblica araba siriana 1
Totale 10.819
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Città #
Dallas 1.786
Chandler 571
Singapore 358
Santa Clara 290
Hefei 267
Bengaluru 265
Milan 262
Princeton 252
Lawrence 251
Ashburn 189
Munich 154
Ho Chi Minh City 140
Wilmington 134
London 113
Beijing 97
Chicago 97
Ottawa 88
Des Moines 86
São Paulo 73
Hanoi 64
Helsinki 50
Los Angeles 49
Shanghai 45
Catanzaro 42
Boardman 31
Hong Kong 30
The Dalles 28
New York 24
Norwalk 24
Rio de Janeiro 22
Guangzhou 21
Shenzhen 21
Da Nang 20
Haiphong 19
Pune 19
Brooklyn 18
Curitiba 18
Turku 18
Rome 17
Tokyo 17
Washington 17
Council Bluffs 16
San Francisco 16
West Jordan 16
Guayaquil 15
Johannesburg 15
Bonn 14
Redwood City 14
Columbus 13
Jiaxing 13
Napoli 13
Porto Alegre 13
Redmond 13
Thái Bình 13
Amsterdam 12
Biên Hòa 12
Palermo 12
Brasília 11
Buffalo 11
Jakarta 11
Olomouc 11
Ribeirão Preto 11
Campinas 10
Guarulhos 10
Montevideo 10
Stockholm 10
Belo Horizonte 9
Boston 9
Ankara 8
Atlanta 8
Chennai 8
Hanover 8
Lấp Vò 8
Quito 8
Seattle 8
Augusta 7
Cagliari 7
Denver 7
Latina 7
Manaus 7
Naples 7
Ninh Bình 7
Phoenix 7
Salvador 7
San Nicola Manfredi 7
Santo André 7
Secaucus 7
Thái Nguyên 7
Wuhan 7
Huế 6
Medellín 6
Montreal 6
Mumbai 6
Reggio Calabria 6
Toronto 6
Warsaw 6
Weihai 6
Avola 5
Bari 5
Buenos Aires 5
Totale 6.637
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 616
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 508
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 480
GBPM: applicazione al docking molecolare 82
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 80
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 73
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 71
A Computational pathway toward the rational design of azinomycin analogues 69
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 68
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 68
Chemioterapici antifungini 66
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 64
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 64
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 63
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 63
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 62
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 62
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 62
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 61
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 60
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 60
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 59
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 59
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 59
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 58
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 58
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 57
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 55
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 54
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 54
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 54
Computer-based techniques for lead identification and optimization II: Advanced search methods 53
CoMFA studies of non covalent monoamine oxidase inhibitors 52
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 51
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 51
GRID-based Pharmacophore Models:Concept and Application Examples 51
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 51
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 51
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 50
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 50
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 50
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 49
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 49
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 49
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 49
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 49
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 49
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 49
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 48
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 48
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning 48
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 48
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 47
MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers 47
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 46
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 46
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 46
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 45
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 45
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 45
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 44
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 44
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 44
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation 43
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 43
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 43
Conformational search of antisense nucleotides 43
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs 43
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 42
Conformational behavior of antineoplastic peptides dolastatin 10 and dolastatin 15 from Monte Carlo and molecular dynamics simulations molecular dynamics simulations 42
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 42
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 41
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 41
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 41
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 41
Identification of new G-quadruplex binders by combined virtual screening approaches. 41
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 41
Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold 41
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives 41
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 40
Composti per il G-quadruplex a struttura naftilimmidica 40
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 40
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 39
Metodi computazionali e nutraceutica 39
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor 39
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 39
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 39
Coumarin versus chromone monoamine oxidase B inhibitors: Quo vadis? 39
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 39
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 38
Rational drug design of Azinomycin analogs 38
Progettazione razionale, sintesi e valutazione enzimatica di ligandi selettivi per le colinesterasi 38
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors 38
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 37
Rational Identification of Ritonavir as IL-20 Receptor A Ligand Endowed with Antiproliferative Properties in Breast Cancer Cells 37
Conformational search of antisense nucleotides. Part 2 37
PTPRJ ligands identification and characterization 37
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 37
Monte Carlo simulation of DNA - azinomycin B interaction: case study of CPU intensive calculations distributed on UNIX platforms 37
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins 37
Totale 6.386
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Categoria #
all - tutte 108.582
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 108.582
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021165 0 0 0 0 26 22 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.774 516 71 47 138 202 146 14 131 283 97 103 26
2023/2024761 111 102 75 58 44 193 24 36 17 35 22 44
2024/20252.766 371 254 133 107 135 337 98 118 363 270 186 394
2025/20264.555 236 851 1.913 1.225 330 0 0 0 0 0 0 0
Totale 10.948