IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 3.270
AS - Asia 1.557
EU - Europa 1.385
SA - Sud America 106
AF - Africa 15
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 1
Totale 6.343
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Nazione #
US - Stati Uniti d'America 3.152
SG - Singapore 1.014
IT - Italia 633
CN - Cina 366
DE - Germania 189
SE - Svezia 166
GB - Regno Unito 149
CA - Canada 103
BR - Brasile 89
FI - Finlandia 76
IN - India 69
UA - Ucraina 48
HK - Hong Kong 29
EE - Estonia 22
NL - Olanda 19
ES - Italia 17
TR - Turchia 14
JP - Giappone 13
CZ - Repubblica Ceca 11
MX - Messico 11
FR - Francia 9
VN - Vietnam 9
RO - Romania 8
PL - Polonia 7
BD - Bangladesh 6
EU - Europa 6
IL - Israele 6
AT - Austria 5
CL - Cile 4
GR - Grecia 4
IR - Iran 4
RU - Federazione Russa 4
SA - Arabia Saudita 4
TW - Taiwan 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AL - Albania 3
AR - Argentina 3
CO - Colombia 3
DK - Danimarca 3
IE - Irlanda 3
KE - Kenya 3
MA - Marocco 3
UY - Uruguay 3
ZA - Sudafrica 3
AE - Emirati Arabi Uniti 2
EG - Egitto 2
IQ - Iraq 2
JO - Giordania 2
LT - Lituania 2
MY - Malesia 2
NP - Nepal 2
PH - Filippine 2
PK - Pakistan 2
PT - Portogallo 2
VE - Venezuela 2
AU - Australia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
GT - Guatemala 1
GY - Guiana 1
JM - Giamaica 1
KZ - Kazakistan 1
MC - Monaco 1
MD - Moldavia 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
PE - Perù 1
PR - Porto Rico 1
PS - Palestinian Territory 1
RE - Reunion 1
TN - Tunisia 1
UZ - Uzbekistan 1
Totale 6.343
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Città #
Chandler 571
Singapore 347
Santa Clara 284
Milan 257
Princeton 252
Lawrence 251
Ashburn 160
Munich 145
Wilmington 134
London 112
Chicago 96
Ottawa 88
Des Moines 86
Helsinki 50
Shanghai 45
Catanzaro 42
Los Angeles 33
The Dalles 28
Norwalk 24
Hong Kong 22
Guangzhou 21
Shenzhen 21
Beijing 20
Boardman 19
Pune 19
Turku 18
Washington 17
West Jordan 16
Bonn 14
New York 14
Redwood City 14
Rome 14
Columbus 13
Council Bluffs 13
Jiaxing 13
Napoli 13
Redmond 13
San Francisco 13
Brooklyn 12
Palermo 12
São Paulo 12
Amsterdam 11
Olomouc 11
Buffalo 10
Tokyo 10
Hanover 8
Seattle 8
Boston 7
Cagliari 7
Dallas 7
Latina 7
Naples 7
San Nicola Manfredi 7
Secaucus 7
Wuhan 7
Augusta 6
Phoenix 6
Reggio Calabria 6
Warsaw 6
Weihai 6
Atlanta 5
Avola 5
Bari 5
Florence 5
Jyväskylä 5
Luni 5
Messina 5
Mountain View 5
Rui'an 5
Shaoxing 5
Siena 5
Taranto 5
Teramo 5
Vasto 5
Xi'an 5
Anagni 4
Ankara 4
Ann Arbor 4
Aversa 4
Bologna 4
Castrovillari 4
Charlotte 4
Chennai 4
Clearwater 4
Cosenza 4
Fuzhou 4
Horia 4
Istanbul 4
Paris 4
Santander 4
Taizhou 4
Toronto 4
Wuxi 4
Afragola 3
Belo Horizonte 3
Catania 3
Chandigarh 3
Como 3
Dongyang 3
Ferrara 3
Totale 3.660
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 209
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 79
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 77
GBPM: applicazione al docking molecolare 72
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 64
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 63
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 59
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 53
A Computational pathway toward the rational design of azinomycin analogues 52
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 52
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 50
Chemioterapici antifungini 50
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 49
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 47
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 47
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 46
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 45
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 45
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 44
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 44
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 43
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 43
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 43
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 41
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 41
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 41
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 40
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 40
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 40
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 40
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 40
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 40
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 39
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 39
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 39
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 38
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 38
Computer-based techniques for lead identification and optimization II: Advanced search methods 38
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 38
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 38
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 37
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 36
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 36
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 36
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 35
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 35
Conformational search of antisense nucleotides 35
CoMFA studies of non covalent monoamine oxidase inhibitors 35
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 35
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 34
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 33
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 33
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 33
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 33
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 32
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 32
Metodi computazionali e nutraceutica 32
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 32
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 32
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 32
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 31
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 31
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 31
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 31
Computational methods applied to the discovery of stem cell factor ligands 30
Donepezil analogs as acetylcholinesterase inhibitors 30
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 30
Computational study on DNA G-quadruplex binding compounds 30
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 30
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 30
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study 30
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 30
Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds 29
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 29
Sintesi di cicloalchilidenidrazo-4-ariltiazoli ad elevata attività inibitrice selettiva sulla isoforma B delle monoamminossidasi 29
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 29
Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors 29
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 29
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 28
Conformational search of antisense nucleotides. Part 2 28
The active site of acetylcholinesterase: validation of a new computational model 28
Chromatographic studies of chiral discrimination by cellulose tris(4-methylbenzoate) 28
Identification of new G-quadruplex binders by combined virtual screening approaches. 28
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 28
null 28
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 28
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation 27
Identification of SET/EED dual binders as innovative PRC2 inhibitors 27
MOLINE docking experiments of enzyme-ligand complexes 27
Enzymatic and molecular modeling studies of 5-HT3 receptor ligands based on pyrroloquinoline structure and provided with acetylcholinesterase inhibitory activity 27
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents 27
Analisi “GRID di antitumorali di derivazione naturale 27
Computational approaches for discovery and optimization of G-quadruplex binders 27
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 27
GRID-based Pharmacophore Models:Concept and Application Examples 26
Development of Selenium based molecular mechanics parameters: an application to antisense nucleotides 26
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells. 26
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 26
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 26
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 26
Totale 3.858
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Categoria #
all - tutte 96.055
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 96.055
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021219 11 7 9 27 26 22 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.774 516 71 47 138 202 146 14 131 283 97 103 26
2023/2024761 111 102 75 58 44 193 24 36 17 35 22 44
2024/20252.766 371 254 133 107 135 337 98 118 363 270 186 394
2025/202677 77 0 0 0 0 0 0 0 0 0 0 0
Totale 6.470