IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 3.974
AS - Asia 1.923
EU - Europa 1.438
SA - Sud America 195
AF - Africa 25
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 3
Totale 7.567
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Nazione #
US - Stati Uniti d'America 3.839
SG - Singapore 1.041
IT - Italia 641
CN - Cina 631
DE - Germania 198
SE - Svezia 171
BR - Brasile 169
GB - Regno Unito 166
CA - Canada 112
IN - India 78
FI - Finlandia 76
UA - Ucraina 51
HK - Hong Kong 36
EE - Estonia 22
VN - Vietnam 22
ES - Italia 21
NL - Olanda 20
TR - Turchia 20
JP - Giappone 16
MX - Messico 16
BD - Bangladesh 14
CZ - Repubblica Ceca 11
FR - Francia 11
IQ - Iraq 9
AR - Argentina 8
IL - Israele 8
PL - Polonia 8
RO - Romania 8
SA - Arabia Saudita 8
ZA - Sudafrica 8
EU - Europa 6
AT - Austria 5
PK - Pakistan 5
RU - Federazione Russa 5
TW - Taiwan 5
CL - Cile 4
GR - Grecia 4
IR - Iran 4
JO - Giordania 4
KE - Kenya 4
MA - Marocco 4
UY - Uruguay 4
UZ - Uzbekistan 4
VE - Venezuela 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AE - Emirati Arabi Uniti 3
AL - Albania 3
CO - Colombia 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
ID - Indonesia 3
IE - Irlanda 3
LT - Lituania 3
AU - Australia 2
EG - Egitto 2
MY - Malesia 2
NP - Nepal 2
PH - Filippine 2
PT - Portogallo 2
TN - Tunisia 2
AZ - Azerbaigian 1
BG - Bulgaria 1
BY - Bielorussia 1
DZ - Algeria 1
GA - Gabon 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
JM - Giamaica 1
KW - Kuwait 1
KZ - Kazakistan 1
MC - Monaco 1
MD - Moldavia 1
MK - Macedonia 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
PE - Perù 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PW - Palau 1
PY - Paraguay 1
RE - Reunion 1
SY - Repubblica araba siriana 1
Totale 7.567
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Città #
Chandler 571
Dallas 571
Singapore 356
Santa Clara 288
Hefei 267
Milan 260
Princeton 252
Lawrence 251
Ashburn 179
Munich 154
Wilmington 134
London 113
Chicago 97
Ottawa 88
Des Moines 86
Helsinki 50
Shanghai 45
Los Angeles 44
Catanzaro 42
Boardman 31
Hong Kong 29
The Dalles 28
Norwalk 24
Guangzhou 21
New York 21
Shenzhen 21
Beijing 20
São Paulo 20
Pune 19
Turku 18
Brooklyn 17
Washington 17
Council Bluffs 16
Rome 16
West Jordan 16
Bonn 14
Redwood City 14
San Francisco 14
Columbus 13
Jiaxing 13
Napoli 13
Redmond 13
Tokyo 13
Amsterdam 12
Palermo 12
Buffalo 11
Olomouc 11
Boston 8
Hanover 8
Seattle 8
Ankara 7
Atlanta 7
Augusta 7
Cagliari 7
Hanoi 7
Ho Chi Minh City 7
Latina 7
Naples 7
San Nicola Manfredi 7
Secaucus 7
Stockholm 7
Wuhan 7
Phoenix 6
Reggio Calabria 6
Toronto 6
Warsaw 6
Weihai 6
Avola 5
Bari 5
Chennai 5
Florence 5
Istanbul 5
Jeddah 5
Johannesburg 5
Jyväskylä 5
Luni 5
Manchester 5
Messina 5
Montreal 5
Mountain View 5
Mumbai 5
Rui'an 5
Shaoxing 5
Siena 5
Taranto 5
Teramo 5
Vasto 5
Xi'an 5
Amman 4
Anagni 4
Ann Arbor 4
Aversa 4
Bologna 4
Castrovillari 4
Charlotte 4
Clearwater 4
Cosenza 4
Fuzhou 4
Horia 4
Las Vegas 4
Totale 4.626
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 332
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 196
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 183
GBPM: applicazione al docking molecolare 74
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 66
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 65
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 63
A Computational pathway toward the rational design of azinomycin analogues 61
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 58
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 58
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 58
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 57
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 56
Chemioterapici antifungini 56
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 56
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 54
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 52
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 52
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 51
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 51
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 50
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 50
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 48
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 47
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 46
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 46
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 45
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 44
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 44
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 44
CoMFA studies of non covalent monoamine oxidase inhibitors 44
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 44
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 44
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 43
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 43
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 43
Computer-based techniques for lead identification and optimization II: Advanced search methods 43
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 42
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 42
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 42
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 41
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 41
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 41
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 41
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 40
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 40
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 40
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 40
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 39
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 39
Conformational search of antisense nucleotides 39
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 39
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 38
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 38
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 38
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 37
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 37
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 37
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 37
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 36
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 35
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 35
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 34
Sintesi di cicloalchilidenidrazo-4-ariltiazoli ad elevata attività inibitrice selettiva sulla isoforma B delle monoamminossidasi 34
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 34
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 34
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study 34
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 34
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 33
Metodi computazionali e nutraceutica 33
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 33
Identification of new G-quadruplex binders by combined virtual screening approaches. 33
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 33
Composti per il G-quadruplex a struttura naftilimmidica 33
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 33
Computational methods applied to the discovery of stem cell factor ligands 32
Conformational search of antisense nucleotides. Part 2 32
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 32
Enzymatic and molecular modeling studies of 5-HT3 receptor ligands based on pyrroloquinoline structure and provided with acetylcholinesterase inhibitory activity 32
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 32
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 32
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 31
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation 31
Identification of SET/EED dual binders as innovative PRC2 inhibitors 31
Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds 31
Donepezil analogs as acetylcholinesterase inhibitors 31
Chromatographic studies of chiral discrimination by cellulose tris(4-methylbenzoate) 31
Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors 31
Computational study on DNA G-quadruplex binding compounds 31
Analisi “GRID di antitumorali di derivazione naturale 31
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 31
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 30
GRID-based Pharmacophore Models:Concept and Application Examples 30
The active site of acetylcholinesterase: validation of a new computational model 30
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 30
Development of Selenium based molecular mechanics parameters: an application to antisense nucleotides 29
MOLINE docking experiments of enzyme-ligand complexes 29
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 29
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents 29
Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5 diaryl pyrazole inhibitors 28
Totale 4.642
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Categoria #
all - tutte 101.499
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.499
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021201 0 0 9 27 26 22 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.774 516 71 47 138 202 146 14 131 283 97 103 26
2023/2024761 111 102 75 58 44 193 24 36 17 35 22 44
2024/20252.766 371 254 133 107 135 337 98 118 363 270 186 394
2025/20261.301 236 851 214 0 0 0 0 0 0 0 0 0
Totale 7.694