IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 6.774
AS - Asia 3.953
EU - Europa 1.592
SA - Sud America 992
AF - Africa 78
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 4
Totale 13.402
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Nazione #
US - Stati Uniti d'America 6.581
SG - Singapore 1.750
CN - Cina 987
BR - Brasile 777
IT - Italia 707
VN - Vietnam 477
IN - India 355
DE - Germania 209
GB - Regno Unito 179
SE - Svezia 175
CA - Canada 125
HK - Hong Kong 105
AR - Argentina 92
FI - Finlandia 78
UA - Ucraina 61
BD - Bangladesh 47
ID - Indonesia 40
MX - Messico 39
EC - Ecuador 36
IQ - Iraq 31
ZA - Sudafrica 29
NL - Olanda 27
ES - Italia 26
TR - Turchia 25
EE - Estonia 22
CO - Colombia 21
JP - Giappone 21
FR - Francia 19
PY - Paraguay 19
RU - Federazione Russa 17
VE - Venezuela 16
MA - Marocco 15
PK - Pakistan 13
UY - Uruguay 12
CL - Cile 11
CZ - Repubblica Ceca 11
TN - Tunisia 10
SA - Arabia Saudita 9
DO - Repubblica Dominicana 8
IL - Israele 8
JO - Giordania 8
NP - Nepal 8
PL - Polonia 8
RO - Romania 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
TW - Taiwan 7
AT - Austria 6
EU - Europa 6
LT - Lituania 6
PE - Perù 6
AL - Albania 5
AZ - Azerbaigian 5
DZ - Algeria 5
EG - Egitto 5
GT - Guatemala 5
KE - Kenya 5
MY - Malesia 5
GR - Grecia 4
IR - Iran 4
KZ - Kazakistan 4
SY - Repubblica araba siriana 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BG - Bulgaria 3
CR - Costa Rica 3
CY - Cipro 3
DK - Danimarca 3
IE - Irlanda 3
KR - Corea 3
MD - Moldavia 3
PA - Panama 3
PH - Filippine 3
PR - Porto Rico 3
AU - Australia 2
BH - Bahrain 2
BY - Bielorussia 2
GA - Gabon 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
MN - Mongolia 2
NG - Nigeria 2
PS - Palestinian Territory 2
PT - Portogallo 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
AO - Angola 1
BO - Bolivia 1
CI - Costa d'Avorio 1
GE - Georgia 1
GH - Ghana 1
GY - Guiana 1
HN - Honduras 1
KH - Cambogia 1
KW - Kuwait 1
LB - Libano 1
MC - Monaco 1
MK - Macedonia 1
NI - Nicaragua 1
Totale 13.391
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Città #
Dallas 1.780
San Jose 981
Chandler 571
Ashburn 500
Singapore 441
Santa Clara 319
Milan 268
Hefei 265
Bengaluru 263
Princeton 252
Lawrence 251
Ho Chi Minh City 171
Beijing 164
Munich 153
Wilmington 134
London 114
Chicago 97
Hong Kong 97
Ottawa 88
Des Moines 86
Hanoi 83
São Paulo 76
Los Angeles 70
Helsinki 52
Shanghai 47
Catanzaro 43
New York 35
Boardman 32
The Dalles 31
Rome 28
Haiphong 26
Norwalk 24
Da Nang 23
Rio de Janeiro 23
Shenzhen 23
Guangzhou 22
Pune 19
Brooklyn 18
Curitiba 18
Johannesburg 18
Tokyo 18
Turku 18
Washington 17
Amsterdam 16
Biên Hòa 16
Council Bluffs 16
San Francisco 16
West Jordan 16
Guayaquil 15
Bonn 14
Redwood City 14
Thái Bình 14
Columbus 13
Jiaxing 13
Napoli 13
Porto Alegre 13
Redmond 13
Buffalo 12
Palermo 12
Ribeirão Preto 12
Bari 11
Brasília 11
Chennai 11
Jakarta 11
Mexico City 11
Montevideo 11
Campinas 10
Guarulhos 10
Olomouc 10
Orem 10
Stockholm 10
Ankara 9
Atlanta 9
Belo Horizonte 9
Boston 9
Denver 9
Quito 9
Santo André 9
Seattle 9
Toronto 9
Hanover 8
Lấp Vò 8
Manaus 8
Montreal 8
Naples 8
Wuhan 8
Amman 7
Augusta 7
Baghdad 7
Buenos Aires 7
Cagliari 7
Can Tho 7
Caracas 7
Florence 7
Huế 7
Hải Dương 7
Istanbul 7
Latina 7
Manchester 7
Ninh Bình 7
Totale 8.340
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 639
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 529
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 502
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 110
GBPM: applicazione al docking molecolare 93
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 92
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 91
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 88
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 85
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 84
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 84
A Computational pathway toward the rational design of azinomycin analogues 83
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 79
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 79
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 78
Computer-based techniques for lead identification and optimization II: Advanced search methods 78
Chemioterapici antifungini 76
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 76
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 76
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 75
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 75
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 74
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 74
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 73
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 71
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 71
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 71
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 71
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 70
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 69
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 68
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 67
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 65
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 65
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 65
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 65
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 64
CoMFA studies of non covalent monoamine oxidase inhibitors 64
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 64
MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers 64
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 63
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 63
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 63
GRID-based Pharmacophore Models:Concept and Application Examples 62
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 62
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 62
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 61
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 61
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 61
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 61
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 60
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 59
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 59
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 59
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 58
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning 58
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 58
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 57
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 57
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 56
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 56
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 55
Identification of new G-quadruplex binders by combined virtual screening approaches. 55
Identification of SET/EED dual binders as innovative PRC2 inhibitors 54
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 54
Metodi computazionali e nutraceutica 54
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 54
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 54
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 53
Conformational search of antisense nucleotides 53
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 53
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 53
Composti per il G-quadruplex a struttura naftilimmidica 53
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 52
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 52
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor 52
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 52
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 51
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 51
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 50
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties 50
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 50
Design, synthesis, and SAR analysis of novel selective sigma(1) ligands 50
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives 50
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 49
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 49
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 49
Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold 49
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs 49
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 49
8-Amide and 8-Carbamate Substitution Patterns as Modulators of 7-Hydroxy-4-Methylcoumarin{'}s Antidepressant Profile: Synthesis, MAO Inhibition, Cytotoxicity and Docking Studies 48
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 48
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 48
Docking e virtual screening su composti naturali: esempi su quercitina e cucurbitacina 48
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 48
Coumarin versus chromone monoamine oxidase B inhibitors: Quo vadis? 48
Conformational behavior of antineoplastic peptides dolastatin 10 and dolastatin 15 from Monte Carlo and molecular dynamics simulations molecular dynamics simulations 47
The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing 47
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins 47
β-cyclodextrin interactions with three drugs used in inflammatory pathologies: an experimental and theoretical study 47
Totale 7.698
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Categoria #
all - tutte 121.792
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 121.792
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202111 0 0 0 0 0 0 0 0 0 0 0 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.768 516 71 47 137 202 146 14 131 281 96 101 26
2023/2024753 109 99 75 57 44 192 24 36 17 35 22 43
2024/20252.745 369 254 132 105 133 336 97 118 360 270 182 389
2025/20267.182 233 845 1.901 1.220 503 192 612 388 730 372 145 41
Totale 13.540