IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 7.056
AS - Asia 3.989
EU - Europa 1.609
SA - Sud America 1.001
Continente sconosciuto - Info sul continente non disponibili 147
AF - Africa 78
OC - Oceania 4
Totale 13.884
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Nazione #
US - Stati Uniti d'America 6.859
SG - Singapore 1.757
CN - Cina 1.004
BR - Brasile 783
IT - Italia 714
VN - Vietnam 477
IN - India 355
DE - Germania 209
GB - Regno Unito 179
SE - Svezia 175
CA - Canada 128
HK - Hong Kong 112
AR - Argentina 93
FI - Finlandia 78
UA - Ucraina 63
BD - Bangladesh 52
ID - Indonesia 40
MX - Messico 39
EC - Ecuador 36
IQ - Iraq 31
ES - Italia 30
ZA - Sudafrica 29
NL - Olanda 27
TR - Turchia 25
CO - Colombia 22
EE - Estonia 22
JP - Giappone 21
FR - Francia 20
PY - Paraguay 19
RU - Federazione Russa 17
VE - Venezuela 17
MA - Marocco 15
PK - Pakistan 13
UY - Uruguay 12
CL - Cile 11
CZ - Repubblica Ceca 11
TN - Tunisia 10
PL - Polonia 9
SA - Arabia Saudita 9
AT - Austria 8
DO - Repubblica Dominicana 8
IL - Israele 8
JO - Giordania 8
NP - Nepal 8
RO - Romania 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
TW - Taiwan 7
EU - Europa 6
LT - Lituania 6
PE - Perù 6
AL - Albania 5
AZ - Azerbaigian 5
DZ - Algeria 5
EG - Egitto 5
GT - Guatemala 5
KE - Kenya 5
MY - Malesia 5
CR - Costa Rica 4
GR - Grecia 4
IR - Iran 4
KZ - Kazakistan 4
SY - Repubblica araba siriana 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BG - Bulgaria 3
CY - Cipro 3
DK - Danimarca 3
IE - Irlanda 3
KR - Corea 3
MD - Moldavia 3
PA - Panama 3
PH - Filippine 3
PR - Porto Rico 3
AU - Australia 2
BH - Bahrain 2
BY - Bielorussia 2
GA - Gabon 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
MN - Mongolia 2
NG - Nigeria 2
PS - Palestinian Territory 2
PT - Portogallo 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
AO - Angola 1
BO - Bolivia 1
CI - Costa d'Avorio 1
GE - Georgia 1
GH - Ghana 1
GY - Guiana 1
HN - Honduras 1
KH - Cambogia 1
KW - Kuwait 1
LB - Libano 1
MC - Monaco 1
MK - Macedonia 1
NI - Nicaragua 1
Totale 13.735
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Città #
Dallas 1.781
San Jose 982
Chandler 571
Ashburn 505
Singapore 446
Santa Clara 328
Milan 271
Hefei 265
Bengaluru 263
Princeton 252
Lawrence 251
Council Bluffs 239
Beijing 176
Ho Chi Minh City 171
Munich 153
Wilmington 134
London 114
Hong Kong 104
Chicago 97
Ottawa 89
Des Moines 86
Hanoi 83
São Paulo 78
Los Angeles 72
Helsinki 52
Shanghai 48
Catanzaro 43
New York 36
Boardman 32
The Dalles 31
Rome 28
Haiphong 26
Norwalk 24
Rio de Janeiro 24
Da Nang 23
Shenzhen 23
Guangzhou 22
Pune 19
Brooklyn 18
Curitiba 18
Johannesburg 18
Tokyo 18
Turku 18
San Francisco 17
Washington 17
Amsterdam 16
Biên Hòa 16
West Jordan 16
Guayaquil 15
Bonn 14
Redwood City 14
Thái Bình 14
Columbus 13
Jiaxing 13
Napoli 13
Porto Alegre 13
Redmond 13
Buffalo 12
Palermo 12
Ribeirão Preto 12
Atlanta 11
Bari 11
Brasília 11
Chennai 11
Jakarta 11
Mexico City 11
Montevideo 11
Boston 10
Campinas 10
Guarulhos 10
Olomouc 10
Orem 10
Seattle 10
Stockholm 10
Ankara 9
Belo Horizonte 9
Denver 9
Montreal 9
Quito 9
Santo André 9
Toronto 9
Hanover 8
Lấp Vò 8
Manaus 8
Naples 8
Phoenix 8
Wuhan 8
Amman 7
Augusta 7
Baghdad 7
Buenos Aires 7
Cagliari 7
Can Tho 7
Caracas 7
Florence 7
Huế 7
Hải Dương 7
Istanbul 7
Latina 7
Manchester 7
Totale 8.621
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Nome #
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 646
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 531
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 504
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 114
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 98
GBPM: applicazione al docking molecolare 94
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 93
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 90
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 86
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 86
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 85
A Computational pathway toward the rational design of azinomycin analogues 83
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 80
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 80
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 79
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 79
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 79
Computer-based techniques for lead identification and optimization II: Advanced search methods 79
Chemioterapici antifungini 78
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 77
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 76
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 76
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 75
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 75
A Pipeline To Enhance Ligand Virtual Screening: Integrating Molecular Dynamics and Fingerprints for Ligand and Proteins 74
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 74
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 72
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 72
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 71
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 69
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 69
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 68
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 67
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 67
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 66
CoMFA studies of non covalent monoamine oxidase inhibitors 66
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 66
Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration 65
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 65
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 65
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 64
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 64
MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers 64
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 63
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 63
Preparation, characterization,molecular modeling and in vitro activity of paclitaxel cyclodextrin complexes 63
GRID-based Pharmacophore Models:Concept and Application Examples 62
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 62
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 62
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach 61
GBPM analysis of HIV-1 reverse transcriptase–DNA crystallographic complexes focused on the enzyme conserved regions of HAART-treated patients 61
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 60
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 60
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 60
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 59
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 59
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b5 reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning 59
Multi-targeting bioactive compounds extracted from essential oils as kinase inhibitors 59
PTPRJ agonist peptides effectively inhibit in vitro cancer cell proliferation and tube formation 58
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 57
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 57
Esterase molecular recognition of small ligands by means of the MOLINE docking methodology 56
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 55
Conformational search of antisense nucleotides 55
Metodi computazionali e nutraceutica 55
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 55
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 55
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 55
Identification of new G-quadruplex binders by combined virtual screening approaches. 55
Identification of SET/EED dual binders as innovative PRC2 inhibitors 54
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 54
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 54
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 54
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor 54
Composti per il G-quadruplex a struttura naftilimmidica 54
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 53
Progettazione razionale di agenti bisalchilanti del DNA analoghi delle azinomicine 53
Dinamica molecolare di complessi della proteasi di HIV-1: influenza di mutazioni associate a resistenza sulla ricognizione molecolare 52
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 52
A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern 51
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties 51
Studi computazionali su modelli di Trascrittasi Inversa del virus HIV 51
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 51
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives 51
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 50
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 50
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 50
Design, synthesis, and SAR analysis of novel selective sigma(1) ligands 50
Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold 50
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs 50
8-Amide and 8-Carbamate Substitution Patterns as Modulators of 7-Hydroxy-4-Methylcoumarin{'}s Antidepressant Profile: Synthesis, MAO Inhibition, Cytotoxicity and Docking Studies 49
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 49
Coumarin versus chromone monoamine oxidase B inhibitors: Quo vadis? 49
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 48
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 48
Docking e virtual screening su composti naturali: esempi su quercitina e cucurbitacina 48
Conformational behavior of antineoplastic peptides dolastatin 10 and dolastatin 15 from Monte Carlo and molecular dynamics simulations molecular dynamics simulations 48
The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing 48
β-cyclodextrin interactions with three drugs used in inflammatory pathologies: an experimental and theoretical study 48
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents 48
Totale 7.829
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Categoria #
all - tutte 126.631
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 126.631
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022643 0 5 13 137 43 20 22 138 72 52 126 15
2022/20231.768 516 71 47 137 202 146 14 131 281 96 101 26
2023/2024753 109 99 75 57 44 192 24 36 17 35 22 43
2024/20252.745 369 254 132 105 133 336 97 118 360 270 182 389
2025/20267.199 233 845 1.901 1.220 503 192 612 388 730 372 145 58
2026/2027327 83 244 0 0 0 0 0 0 0 0 0 0
Totale 13.884