IRIS
ORTUSO, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 2.608
EU - Europa 714
AS - Asia 98
SA - Sud America 21
Continente sconosciuto - Info sul continente non disponibili 9
AF - Africa 3
OC - Oceania 1
Totale 3.454
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Nazione #
US - Stati Uniti d'America 2.506
IT - Italia 291
SE - Svezia 164
GB - Regno Unito 128
CA - Canada 94
IN - India 53
UA - Ucraina 47
DE - Germania 33
BR - Brasile 12
RO - Romania 8
FR - Francia 7
EU - Europa 6
IL - Israele 6
MX - Messico 6
TR - Turchia 6
CN - Cina 5
ES - Italia 5
FI - Finlandia 5
HK - Hong Kong 5
SG - Singapore 5
CL - Cile 4
GR - Grecia 4
IR - Iran 4
RU - Federazione Russa 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AT - Austria 3
DK - Danimarca 3
JP - Giappone 3
NL - Olanda 3
TW - Taiwan 3
CO - Colombia 2
IE - Irlanda 2
MY - Malesia 2
PH - Filippine 2
PT - Portogallo 2
UY - Uruguay 2
VN - Vietnam 2
AL - Albania 1
AU - Australia 1
BG - Bulgaria 1
DO - Repubblica Dominicana 1
EG - Egitto 1
MC - Monaco 1
MD - Moldavia 1
MN - Mongolia 1
NG - Nigeria 1
NO - Norvegia 1
NP - Nepal 1
PE - Perù 1
PR - Porto Rico 1
RE - Reunion 1
Totale 3.454
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Città #
Chandler 571
Princeton 252
Lawrence 251
Wilmington 134
Ashburn 132
London 109
Ottawa 88
Des Moines 86
Chicago 85
Catanzaro 42
Norwalk 24
Pune 19
Washington 17
West Jordan 16
Bonn 14
Redwood City 14
Napoli 13
Redmond 13
Boardman 12
Los Angeles 10
Hanover 8
Latina 7
Palermo 7
Naples 6
Reggio Calabria 6
Rome 6
Seattle 6
São Paulo 6
Augusta 5
Avola 5
Cagliari 5
Helsinki 5
Luni 5
Messina 5
Mountain View 5
Singapore 5
Teramo 5
Ann Arbor 4
Bologna 4
Buffalo 4
Castrovillari 4
Clearwater 4
Cosenza 4
Horia 4
Milan 4
Secaucus 4
Catania 3
Como 3
Giulianova 3
Gopalganj 3
Rende 3
Salsomaggiore 3
San Cristóbal de La Laguna 3
Santa Clara 3
Siena 3
Amaroni 2
Andover 2
Bari 2
Bathinda 2
Bogotá 2
Brindisi 2
Ca Mau 2
Caulonia 2
Chandigarh 2
Cisterna di Latina 2
Dallas 2
Dublin 2
Erzurum 2
Eskisehir 2
Essen 2
Florence 2
Grottaglie 2
Jinan 2
Kuala Lumpur 2
Leawood 2
Leeds 2
Manziana 2
Marano 2
Marina Di Gioiosa 2
Milazzo 2
Montevideo 2
Mysore 2
Pachino 2
Paris 2
Pavia 2
Pescara 2
Peterborough 2
Phoenix 2
Pontedera 2
San Francisco 2
Santander 2
Serra San Bruno 2
Soverato Marina 2
Taipei 2
Vasto 2
Vienna 2
Ahmedabad 1
Amsterdam 1
Asbest 1
Berlin 1
Totale 2.148
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Nome #
GBPM: applicazione al docking molecolare 60
La cipolla rossa di Tropea (Allium cepa L.): attività farmacologica e prospettive terapeutiche dei suoi fitocomposti in un modello comportamentale animale 55
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors 55
1- acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazole; a new scaffold for monoaminoxidase inhibitors: design, synthesis, and biological properties 51
1-benzenesulfonamide-1(H)-pyrazoles and 3-benzenesulfonamide-4-tiazolidinones, two promising scaffolds for the design of cycloxygenase inhibitors 49
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. 37
Chemioterapici antifungini 35
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile 34
Back Cover: Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016) 32
4-carbossamido-9-fluorenoni: proprietà anti-HSV-2 e immunostimolanti 32
Approccio GRID per lo sviluppo alternativo di modelli farmacoforici 32
Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia 32
9-fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II 31
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 31
A Computational pathway toward the rational design of azinomycin analogues 30
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 30
From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds 29
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 29
In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes 29
Isolation and Functional Characterization of Peptide Agonists of PTPRJ, a Tyrosine Phosphatase Receptor Endowed with Tumor Suppressor Activity. 29
SGK1, the serum- and glucocorticoid-regulated kinase, modulates the response to taxanes by regulating the GTPase RAN and its partners in colon carcinoma cells. 28
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold 28
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques 28
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis 27
Synthesis, stereo chemical identification and selective inhibitory activity against MAO-B of 3-methyl cyclohexylidene-(4-arylthiazol- 2-yl)hydrazones derivatives 27
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization 27
Molecular Modeling and Enzymatic Studies of Acetylcholinesterase and Butyrylcholinesterase recognition with Paraquat and related compounds 26
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B 26
A comparative study of the in vitro inhibitory activity of tacrine-like molecules (Paraquat, MPTP, MPDP and MPP+) on hydrolysis by acetylcholine and butyrylcholine esterases 26
SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation 26
A Comparative Docking Strategy to Identify Polyphenolic Derivatives as Promising Antineoplastic Binders of G-quadruplex DNA c-myc and bcl-2 Sequences 25
Computational analysis of human immunodeficiency virus (HIV) type-1 reverse transcriptase crystallographic models based on significant conserved residues found in highly active antiretroviral therapy (HAART)-treated patients 25
Metodi computazionali e nutraceutica 24
Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species 24
Computer-based techniques for lead identification and optimization II: Advanced search methods 24
A chromatographic and computational study on the driving force operating in the exceptionally large enantioseparation of N-thiocarbamoyl-3-(4'-biphenyl)-5-phenyl-4,5-dihydro-(1H) pyrazole on a 4-methylbenzoate cellulose-based chiral stationary phase 23
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells 23
Simulazioni Monte Carlo delle interazioni tra l'Azinomicina B e il DNA: esempio di calcolo intensivo distribuito su piattaforme UNIX 23
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale σ-1 23
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors 23
CoMFA studies of non covalent monoamine oxidase inhibitors 23
Discovery of PTPRJ Agonist Peptides That Effectively Inhibit in Vitro Cancer Cell Proliferation and Tube Formation. 23
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors 22
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors 22
Computational methods applied to the discovery of stem cell factor ligands 22
Indagine statistica sulla diffusione nell’Industria farmaceutica italiana di tecnologie computazionali avanzate orientate alla progettazione di nuovi farmaci 22
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors 22
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches 22
Selective inhibitory activity against MAO-A of crude extracts and pure compounds of Hypericum hircinum L.: extraction and computational study 22
Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition 22
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 22
Comparison of Computational Methods in Docking Experiments of G-Quadruplex Binders 21
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders 21
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study 21
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones 20
Sintesi di cicloalchilidenidrazo-4-ariltiazoli ad elevata attività inibitrice selettiva sulla isoforma B delle monoamminossidasi 20
Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropein Derivatives as Cox-1 and -2 Inhibitors 20
Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement 20
Molecular recognition of a carboxy pyridostatin towards G-quadruplex structures: why does it prefer RNA? 20
Computational study on DNA G-quadruplex binding compounds 20
Comparison of molecular dynamics simulations carried out on wild type and mutants of HIV-1 reverse transcriptase 20
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome 20
Identification of SET/EED dual binders as innovative PRC2 inhibitors 19
Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties 19
Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase 19
Conformational search of antisense nucleotides 19
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors 19
Identification of new G-quadruplex binders by combined virtual screening approaches. 19
Natural products extracted from fungal species as new potential anti-cancer drugs: A structure-based drug repurposing approach targeting HDAC7 19
Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds 18
Donepezil analogs as acetylcholinesterase inhibitors 18
Drug Design and Synthesis of Tacrine and Donepezil analogs 18
Development of Selenium based molecular mechanics parameters: an application to antisense nucleotides 18
Computational approaches for discovery and optimization of monoamine oxidase B inhibitors 18
Chromatographic studies of chiral discrimination by cellulose tris(4-methylbenzoate) 18
Computational approaches for discovery and optimization of G-quadruplex binders 18
GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods 18
"Synthesis, Biological Evaluation and Molecular Modeling of Natural and Semi-synthetic Oleuropeine Drivates as Cox-l and -2 Inhibitors 18
An approach to address Candida rugosa lipase regioselectivity in the acylation reactions of trytilated glucosides 17
Studies of substituted thiazolylhydrazones as a new scaffold for mao-inhibitory activity 17
Screening virtuale di inibitori selettivi dell’SCF 17
The active site of acetylcholinesterase: validation of a new computational model 17
MOLINE docking experiments of enzyme-ligand complexes 17
Enzymatic and molecular modeling studies of 5-HT3 receptor ligands based on pyrroloquinoline structure and provided with acetylcholinesterase inhibitory activity 17
Antioxidant Efficiency of Oxovitisin, a New Class of Red Wine Pyranoanthocyanins, Revealed through Quantum Mechanical Investigations 17
Progettazione, sintesi e rapporto struttura-attività di ligandi selettivi per il sottotipo recettoriale sigma-1 16
Drug design, synthesis and enzymatic evaluation of selective cholinesterase ligands 16
MOLecular INteraction Evaluation: an original docking methodology applied to drug design 16
Progettazione razionale e sintesi di potenziali inibitori della glutatione S transferasi (GST) 16
Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors 16
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity 16
Multi-target drug discovery: An opportunity for novel and repurposed bioactive compounds 16
Fhit delocalizes Annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel 16
Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors 16
Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5 diaryl pyrazole inhibitors 15
Role of copper ion in the structural and dynamic properties of prion protein 15
Hit identification of novel DNA-quadruplex ligands 15
Synthesis, Biological Evalution and Molecular Modeling of Natural and Semi-Synthetic Oleuropeine Derivatives as Cox-1 and Cox-2 Inhibitors 15
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties 15
Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives 15
Totale 2.363
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Categoria #
all - tutte 53.075
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.075
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020223 0 0 0 4 20 2 18 19 14 11 42 93
2020/2021219 11 7 9 27 26 22 27 8 51 17 3 11
2021/2022650 7 5 13 137 43 20 22 138 72 52 126 15
2022/20231.774 516 71 47 138 202 146 14 131 283 97 103 26
2023/2024695 111 102 75 58 44 193 24 36 17 35 0 0
Totale 3.561